12667-M
Human Serum Albumin
30% Aqueous Solution
Synonym(s):
Albumin, Human Serum, 30% Aqueous Solution
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About This Item
Biological source:
human
Assay:
≥95% (agarose gel electrophoresis)
Form:
liquid
Technique(s):
cell culture | mammalian: suitable
Product Name
Albumin, Human Serum, 30% Aqueous Solution,
biological source
human
Quality Level
description
Merck USA index - 14, 8468
assay
≥95% (agarose gel electrophoresis)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
technique(s)
cell culture | mammalian: suitable
storage temp.
2-8°C
SMILES string
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
General description
Human serum albumin (HSA) is a soluble, globular, and unglycosylated monomeric protein, which is abundantly found in the plasma. It contains three homologous domains, numbered I, II, and III. Each domain is divided into subdomains A and B comprising common structural motifs. The HSA gene is localized to the human chromosome 4q13.3.
Biochem/physiol Actions
Human serum albumin (HSA) acts as the most important carrier protein for fatty acids, thyroid hormones, and steroids. It serves as a supplement in cell culture medium for the generation of vaccines and pharmaceuticals. HSA acts as a valuable biomarker for diseases, such as severe acute graft-versus-host disease, cancer, and rheumatoid arthritis. It is clinically used to treat serious burn injuries, hemorrhagic shock, hypoproteinemia, and fetal erythroblastosis. HSA is used in biological applications including nano delivery of drugs, carrier of oxygen, and fusion of peptides.
Physical form
30% solution in 20 mM Tris-HCl, 0.1% NaN₃, pH 6-8.
Preparation Note
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Toxicity: Standard Handling (A)
Storage Class
10 - Combustible liquids
wgk
WGK 3
Regulatory Information
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Gabriella Fanali et al.
Molecular aspects of medicine, 33(3), 209-290 (2012-01-11)
Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multi-domain macromolecule, representing the main determinant of plasma oncotic pressure and the main modulator of fluid distribution between body compartments. HSA displays an extraordinary ligand binding capacity
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 12667-50ML-M | 04055977222081 |