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Merck
CN

1.41350

Polyvinyl alcohol

4-88, EMPROVE® ESSENTIAL, Ph. Eur., ChP, JPE, USP

Synonym(s):

Poly(vinyl alcohol), PVA, PVOH

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About This Item

Linear Formula:
[-CH2CHOH-]n
CAS Number:
UNSPSC Code:
13111042
MDL number:
Technical Service
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Quality Level

agency

ChP, JPE, Ph. Eur., USP

product line

EMPROVE® ESSENTIAL

form

scales

technique(s)

API processing | nano-milling: suitable

mp

160-240 °C

application(s)

controlled release
liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

General description

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polyvinyl alcohol 4-88 is a synthetic, bio-compatible, toxicologically safe, and multi-compendial polymer. It is part of a portfolio spanning a wide range of pharmaceutical grade polyvinyl alcohols of different viscosities, hydrolysis grades and molecular weights and is well suited for a broad variety of pharmaceutical applications, including solid, liquid, and semi-solid formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

11 - Combustible Solids



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

PVA meets all the essential requirements to be used in ophthalmic preparations and offers important benefits compared to HPMC and CMC.

Learn about common tablet manufacturing technologies and the advantages and disadvantages of each.





Global Trade Item Number

SKUGTIN
141350100004027269063689
141350902904027269074876
141350952504027269142940