178468
Apolipoprotein E, Human Plasma, Very Low-Density Lipoprotein
Native apolipoprotein E from human plasma. A major component of VLDL and IDL. Serves as a major cholesterol carrier. Essential for the normal catabolism of triglyceride-rich lipoprotein constituents.
Synonym(s):
Apo E
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About This Item
NACRES:
NA.25
UNSPSC Code:
12352202
Form:
liquid
Assay:
≥95% (SDS-PAGE)
Quality Level
assay
≥95% (SDS-PAGE)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
shipped in
wet ice
storage temp.
−20°C
General description
Native apolipoprotein E from human plasma. A component of VLDL and of a subclass of HDL. Present in normal plasma at concentrations of 50 µg/ml. Serves as a ligand for LDL receptors, where it participates in the transport and redistribution of cholesterol and other lipids. Also functions in immunoregulation and cell growth differentiation. Inhibits mitogen-induced T-lymphocyte proliferation and modulation of smooth muscle cell differentiation.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In 50 mM NH₄HCO₃, pH 8.0.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
Kelly, M.E., et al. 1994. Cell Immunol. 159, 124.
Mahley, R.W. 1988. Science 240, 622.
Rall, S.C., et al. 1986. Methods Enzymol. 128, 273.
Mahley, R.W. 1988. Science 240, 622.
Rall, S.C., et al. 1986. Methods Enzymol. 128, 273.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
监管及禁止进口产品
This item has
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 178468-50UG | 04055977205169 |