19-142
LY 294002
Synonym(s):
NSC 697286, PI3K inhibitor, SF 1101
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.41
eCl@ss:
32160405
form
solid
Quality Level
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
shipped in
wet ice
Application
Specific and potent inhibitor of PI 3-kinase.
Biochem/physiol Actions
Inhibitor Type: Kinase
Physical form
C19H17NO3
Preparation Note
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
487.4 °F
flash_point_c
253.0 °C
Certificates of Analysis (COA)
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Wen Jiang et al.
Bioengineered, 12(2), 10264-10284 (2021-11-02)
Chronic skin ulcers are a primary global health problem. Velvet antler polypeptide (VAP) regulates endothelial cell migration and angiogenic sprout. Adipose-derived stem cells (ADSCs) are reported to make pivotal impacts upon wound healing. This study aimed to explore the role
C J Vlahos et al.
The Journal of biological chemistry, 269(7), 5241-5248 (1994-02-18)
Phosphatidylinositol (PtdIns) 3-kinase is an enzyme implicated in growth factor signal transduction by associating with receptor and nonreceptor tyrosine kinases, including the platelet-derived growth factor receptor. Inhibitors of PtdIns 3-kinase could potentially give a better understanding of the function and
Satoru Takahashi et al.
The Journal of biological chemistry, 278(33), 30821-30827 (2003-06-12)
Endothelial nitric-oxide synthase (eNOS), which generates the endogenous vasodilator, nitric oxide (NO), is highly regulated by post-translational modifications and protein interactions. We recently used purified proteins to characterize the mechanisms by which heat shock protein 90 (HSP90) increases eNOS activity
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 19-142 | 04053252283116 |