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3570

Glycine

Name: Glycine
Brand: MM

Synonym(s):

Glycine, Gly, Aminoacetic acid, Aminoethanoic acid, Glycocoll

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About This Item

Linear Formula:

NH₂CH₂COOH

CAS Number:

56-40-6

Molecular Weight:

75.07

NACRES:

NA.54

UNSPSC Code:

12352209

Beilstein/REAXYS Number:

635782

MDL number:

MFCD00008131

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Properties

description

RTECS - MB7600000
Merck USA index - 14, 4491

Quality Level

100

assay

>99% (by assay)

form

crystalline solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

impurities

≤100 CFU/g Total microorganism, ≤6.0 EU/g Endotoxin

color

white

pKa (25 °C)

(1) 2.35, (2) 9.60, 2.35

mp

240 °C (dec.) (lit.)

solubility

water: 250 mg/mL

cation traces

Fe: ≤10 ppm, heavy metals (as Pb): ≤5 ppm

shipped in

ambient

storage temp.

15-25°C

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Description

General description

A non-essential, optically inactive, non-chiral amino acid. It is the smallest of the 20 natural amino acids. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons.

A nonpolar, uncharged amino acid.

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Other Notes

Shapiro, S. 1997. Neurosurgery 40, 168.
Mount, H., et al. 1991. Mol. Pharmacol.39, 205.
Thompson, A.M., et al. 1989. Nature338, 422.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

No data available

flash_point_c