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36-008

Anti-α-Synuclein (SNCA) Antibody

Name: Anti-α-Synuclein (SNCA) Antibody
Brand: MM

UPSTATE^®, mouse monoclonal, Syn211

Synonym(s):

Anti-NACP, Anti-PARK1, Anti-PARK4, Anti-PD1

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About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

Clone:

Syn211, monoclonal

Species reactivity:

human

Application:

IHC, IP, WB

Citations:

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Properties

Product Name

Anti-α-Synuclein Antibody, clone Syn211, ascites fluid, clone Syn211, Upstate^®

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

Syn211, monoclonal

species reactivity

human

packaging

antibody small pack of 25 μL

manufacturer/tradename

Upstate^®

technique(s)

immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

NCBI accession no.

NM_000345.2, NM_007308.1

UniProt accession no.

P37840

shipped in

ambient

target post-translational modification

unmodified

Gene Information

human ... SNCA(6622)

Description

General description

~14.5kDa

Immunogen

full-length recombinant human α-Synuclein

Application

Detect α-Synuclein using this Anti-α-Synuclein Antibody, clone Syn211 validated for use in IP, WB, IH.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Biochem/physiol Actions

α-Synuclein

Physical form

Ascites

Preparation Note

2 years at -20°C

Analysis Note

Routinely evaluated by immunoblot on Alzheimer′s diseased human whole brain lysates.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Replaces: 04-1053

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Neuron-to-neuron ?-synuclein propagation in vivo is independent of neuronal injury.

Ulusoy, A; Musgrove, RE; Rusconi, R; Klinkenberg, M; Helwig, M; Schneider, A; Di Monte, DA

Acta Neuropathologica Communications null

Characterization of cognitive deficits in rats overexpressing human alpha-synuclein in the ventral tegmental area and medial septum using recombinant adeno-associated viral vectors.

Hall, H; Jewett, M; Landeck, N; Nilsson, N; Schagerlof, U; Leanza, G; Kirik, D

Testing null

A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease.

B I Giasson et al.

Journal of neuroscience research, 59(4), 528-533 (2000-02-19)

To facilitate studies of the normal biology of alpha-synuclein, a member of a family of neuronal proteins of unknown function, and to elucidate the role of alpha-synuclein pathologies in neurodegenerative diseases, we generated and characterized a panel of anti-synuclein antibodies.

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Global Trade Item Number

SKU	GTIN
36-008-25UL	04054839337352