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391333

HEPES sodium salt

Name: HEPES sodium salt
Brand: MM

ULTROL^® Grade, ≥99% dry basis (titration), zwitterionic N-substituted aminosulfonic acid buffer

Synonym(s):

HEPES, Sodium Salt, ULTROL^® Grade, N-2-Hydroxyethylpiperazine-Nʹ-2-ethanesulfonic Acid, Na

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About This Item

Empirical Formula (Hill Notation):

C₈H₁₇N₂O₄S · Na

CAS Number:

75277-39-3

Molecular Weight:

260.29

MDL number:

MFCD00036463

UNSPSC Code:

12161704

NACRES:

NA.25

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Properties

Quality Level

100

assay

≥99% dry basis (titration)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic)

color

white

pKa (20 °C)

7.6

solubility

water: 1.0 M

anion traces

chloride (Cl^-): <0.01%, sulfate (SO₄^2-): <0.05%

cation traces

heavy metals: <1 ppm

shipped in

ambient

storage temp.

15-25°C

SMILES string

[Na+].[S](=O)(=O)([O-])CCN1CCN(CC1)CCO

InChI

1S/C8H18N2O4S.Na/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;/h11H,1-8H2,(H,12,13,14);/q;+1/p-1

InChI key

RDZTWEVXRGYCFV-UHFFFAOYSA-M

Description

General description

A zwitterionic N-substituted aminosulfonic acid buffer(Absorbance: <0.10 at 260 nm, 1.0 mM, H₂O). Active in the pH range of 6.0 to 8.5. Has a pK_a of 7.6 at 20°C.

Absorbance (1.0 mM, H₂O, 260 nm):<0.10.

Application

3,6-O-[N-(2-Aminoethyl)-acetamide-yl]-chitosan exerts antibacterial activity by a membrane damage mechanism.: This study explores the antibacterial mechanisms of a chitosan derivative, which could be related to the buffering capabilities of HEPES in maintaining the stability and exposure of functional groups necessary for antibacterial activity (Yan et al., 2016).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c