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Merck
CN

5.00117

Choline chloride

EMPROVE® ESSENTIAL, DAB 10

Synonym(s):

Choline chloride

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About This Item

Empirical Formula (Hill Notation):
C5H14ClNO
CAS Number:
Molecular Weight:
139.62
UNSPSC Code:
12352107
EC Index Number:
200-655-4
MDL number:
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agency

DAB 10

Quality Level

product line

EMPROVE® ESSENTIAL

form

solid

autoignition temp.

355 °C

potency

3400 mg/kg LD50, oral (Rat)

pH

4-6 (20 °C, 100 g/L in H2O)

application(s)

pharmaceutical
solid formulation

storage temp.

15-25°C

SMILES string

[Cl-].[N+](CCO)(C)(C)C

InChI

1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

InChI key

SGMZJAMFUVOLNK-UHFFFAOYSA-M

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Choline chloride Emprove® Essential is mainly used in highly regulated pharmaceutical applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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Saeed Hesaraki et al.
Materials science & engineering. C, Materials for biological applications, 109, 110592-110592 (2020-04-02)
Resin-based pit-and-fissure sealants (flowable resin composites) were formulated using bisphenol-A-glycerolatedimethacrylate (Bis-GMA)-triethylene glycol dimethacrylate-(TEGDMA)-diurethanedimethacrylate (UDMA) mixed monomers and multiple fillers, including synthetic strontium fluoride (SrF2) nanoparticles as a fluoride-releasing and antibacterial agent, yttria-stabilized zirconia (YSZ) nanoparticles as an auxiliary filler, and



Global Trade Item Number

SKUGTIN
500117500004022536256061
500117902504022536721682