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538904

Prostaglandin E2

>98% (HPLC), MAP kinase inhibitor, solid

Synonym(s):

Prostaglandin E2, PGE2

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About This Item

Empirical Formula (Hill Notation):
C20H32O5
CAS Number:
363-24-6
Molecular Weight:
352.47
UNSPSC Code:
12352211
NACRES:
NA.77
MDL number:
MFCD00077861
Assay:
>98% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze
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Product Name

Prostaglandin E2, Involved in vasodilator actions of kinins such as bradykinin.

Quality Level

100

description

Merck USA index - 14, 7877

assay

>98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white to light yellow

solubility

acetone: soluble, ethanol: soluble, ethyl acetate: soluble, methanol: soluble

shipped in

wet ice

storage temp.

−20°C

SMILES string

OC1C(C(C(=O)C1)C\C=C\CCCC(=O)O)\C=C\C(O)CCCCC

InChI

1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4+,13-12+

InChI key

XEYBRNLFEZDVAW-RTYMFESYSA-N

General description

Involved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC50 = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Involved in vasodilator actions of kinins such as bradykinin
Product does not compete with ATP.
Reversible: no
Target IC50: 25-50 µM inhibiting MAP kinase in rat mesangial cells

Other Notes

Li, X., et al. 1995. Am. J. Physiol.269, C986.
Kessler, W., et al. 1992. Exp. Brain Res.91, 467.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
538904-1MG07790788051266