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6.08101

Tetrahydrofuran

suitable for chromatography

Synonym(s):

Tetrahydrofuran, THF, Butylene oxide, Oxolane, Tetramethylene oxide

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About This Item

Empirical Formula (Hill Notation):
C4H8O
CAS Number:
109-99-9
Molecular Weight:
72.11
UNSPSC Code:
12352005
Beilstein/REAXYS Number:
102391
MDL number:
MFCD00005356
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vapor density

2.5 (vs air)

Quality Level

100

vapor pressure

114 mmHg ( 15 °C), 143 mmHg ( 20 °C)

autoignition temp.

610 °F

expl. lim.

1.8-11.8 %

refractive index

n20/D 1.407 (lit.)

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

density

0.889 g/mL at 25 °C (lit.)

suitability

suitable for chromatography

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

General description

Tetrahydrofuran(THF) is commonly used as a solvent in liquid chromatography. THF is widelyutilized as a solvent in non-aqueous size-exclusion chromatography (SEC),because it is a good solvent for various polymer types.

Application

Tetrahydrofuran can be used as a mobile-phase component in the:
  • Analysis of tocopherols.
  • HPLC analysis of self-associated cationicpolymer (NREP).

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signalword

Danger

target_organs

Central nervous system, Respiratory system

supp_hazards

EUH019

Storage Class

3 - Flammable liquids

flash_point_f

-6.2 °F - closed cup

flash_point_c

-21.2 °C - closed cup

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3

Regulatory Information

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