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Merck
CN

8.03235

N,N-Dimethylacetamide

for synthesis

Synonym(s):

N,N-Dimethylacetamide, Acetic acid dimethylamide, Acetyldimethylamine, DMA

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About This Item

Linear Formula:
CH3CON(CH3)2
CAS Number:
Molecular Weight:
87.12
UNSPSC Code:
12352111
EC Index Number:
204-826-4
NACRES:
NA.22
MDL number:
Assay:
≥99% (GC)
Grade:
synthesis grade
Bp:
165-166 °C/1013 hPa
Vapor pressure:
1.76 hPa ( 20 °C)
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grade

synthesis grade

Quality Level

vapor pressure

1.76 hPa ( 20 °C)

assay

≥99% (GC)

form

liquid

autoignition temp.

400 °C

potency

5830 mg/kg LD50, oral (Rat)

expl. lim.

1.7-11.5 % (v/v)

dilution

(for synthesis)

pH

4 (20 °C, 200 g/L in H2O)

bp

165-166 °C/1013 hPa

mp

-20 °C

transition temp

flash point 64 °C

solubility

soluble >1000 g/L

density

0.94 g/cm3 at 20 °C

storage temp.

2-30°C

SMILES string

N(C)(C)C(=O)C

InChI

1S/C4H9NO/c1-4(6)5(2)3/h1-3H3

InChI key

FXHOOIRPVKKKFG-UHFFFAOYSA-N

General description

N,N-Dimethylacetamide (DMAc) is a water-miscible organic solvent used in the synthesis of styrene, vinyl resin, linear polyester, acrylic fiber, plastic, pesticide, and synthetic leather. It participates in dehydrogenation, dehydration, halogenation, deprotonation reactions and reductive carbonylation of transition metals. It can also act as catalysts, promoters, halogen/alkoxy or hydroxyl/halogen exchange mediators, reducing agents, and sources of the base.

Application

N,N-Dimethylacetamide is used as a solvent:
  • In the synthesis of poly(amide-hydrazide)s–graphene composites.
  • In the synthesis of N,N′-1,2-ethanediylbis-(4-hydroxy-pentanamide) and 4-hydroxy-N-(2- hydroxyethyl)-pentanamide based polyurethanes in presence of triethylamine catalyst.

Features and Benefits

N,N-Dimethylacetamide has :
  • High dissolution power of various substrate. 
  • High capacity to solvate anions.

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.940 - 0.942
Water (K. F.): ≤ 0.30 %
Identity (IR): passes test


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pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B

wgk

WGK 2

flash_point_f

147.2 °F - closed cup

flash_point_c

64 °C - closed cup

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects



Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
803235005004027269250584
803235902604027269192648
803235100004022536379531
803235250004022536379548