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Merck
CN

8.18731

Salicylic acid

for synthesis

Synonym(s):

Salicylic acid, 2-Hydroxybenzoic acid

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About This Item

Empirical Formula (Hill Notation):
C7H6O3
CAS Number:
Molecular Weight:
138.12
UNSPSC Code:
12352106
EC Index Number:
200-712-3
NACRES:
NA.22
MDL number:
Assay:
≥99% (acidimetric)
Form:
solid
Grade:
synthesis grade
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grade

synthesis grade

Quality Level

vapor pressure

<1 hPa ( 100 °C)

assay

≥99% (acidimetric)

form

solid

autoignition temp.

500 °C

potency

1250-1580 mg/kg LD50, oral (Rat), >2000 mg/kg LD50, skin (Rat)

technique(s)

tissue culture: suitable

pH

2.4 ( in H2O, saturated solution)

bp

211 °C/1013 hPa

mp

157-159 °C

transition temp

flash point 157 °C

solubility

water: 2 g/L at 20 °C

density

1.443 g/cm3 at 20 °C

bulk density

400‑500 kg/m3

storage temp.

2-30°C

SMILES string

[O-]c1c(cccc1)C(=O)O.[H+]

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

InChI key

YGSDEFSMJLZEOE-UHFFFAOYSA-N

Application


  • Salicylic Acid and Water Stress: Investigates the impact of salicylic acid on the morphophysiology and essential oil profile of Eryngium foetidum under water stress conditions, highlighting its role in enhancing plant resilience and secondary metabolite production (Santos et al., 2024).

  • Salicylic Acid in Plant Defense: Focuses on the usage of salicylic acid as an elicitor to boost the production of withanolides and phenolic acids in Withania somnifera, demonstrating its efficacy in improving secondary metabolite yield in plant biotechnological applications (Halder and Ghosh, 2024).

  • Salicylic Acid in Natural Deep Eutectic Solvents: Describes the application of natural deep eutectic solvents containing salicylic acid for forming aqueous biphasic systems, presenting a novel method for drug extraction and highlighting its potential in pharmaceutical manufacturing (Ghaffari et al., 2024).



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Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

314.6 °F - closed cup

flash_point_c

157 °C - closed cup



Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
818731100004022536444123
818731905004022536708737
818731010004022536444116