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Merck
CN

AB1583

Anti-Neuropeptide Y Antibody

serum, Chemicon®

Synonym(s):

NPY

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, RIA
Citations:
58
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biological source

sheep

Quality Level

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

invertebrates, rabbit, guinea pig

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, radioimmunoassay: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

rabbit ... Npy(100301542)

Immunogen

Synthetic NPY peptide conjugated to bovine thyroglobulin.

Application

Detect Neuropeptide Y using this Anti-Neuropeptide Y Antibody validated for use in IH, RIA.
Immunohistochemistry: 1:5,000 on rabbit and guinea pig using an ABC detection method.

RIA

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
CNS Control of Metabolism

Hormones & Receptors

Biochem/physiol Actions

Neuropeptide Y (NPY). The specificity was determined by RIA. Synthetic peptides somatostatin-14, leu-enkephalin, met-enkephalin, oxytocin, Agr8-vasopressin, vasoactive intestinal peptide and angiotensin II showed less than 0.005% cross reactivity and substance P less than 0.02%. Peptide YY and bovine pancreatic polypeptide showed approximately 36% and 0.05% cross reactivity respectively. Human Peptide YY shares 65% homology amino acid sequence for human NPY.



Synthetic NPY completely abolishes radio labeled NPY binding to NPY antibody in RIA and antibody binding to tissue antigen.

Physical form

Sheep serum. Lyophilized, no preservatives. Reconstitute with 100 μL of sterile distilled water.

Preparation Note

Maintain at -20 to -70°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Quantitative study of NPY-expressing GABAergic neurons and axons in rat spinal dorsal horn.
Polgar E, Sardella TC, Watanabe M, Todd AJ
The Journal of Comparative Neurology null
J A Evans et al.
Neuroscience, 202, 300-308 (2011-12-14)
In mammals, light entrains the central pacemaker within the suprachiasmatic nucleus (SCN) through both a direct neuronal projection from the retina and an indirect projection from the intergeniculate leaflet (IGL) of the thalamus. Although light comparable in intensity to moonlight
Enhanced neuropeptide Y immunoreactivity and vasoconstriction in mesenteric small arteries from spontaneously hypertensive rats.
Kathryn A Gradin, Jia-Yi Li, Ove Andersson, Ulf Simonsen
Journal of Vascular Research null



Global Trade Item Number

SKUGTIN
AB158304053252321474