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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
9
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... H2BC1(255626)
Immunogen
Synthetic peptide
Application
Detect Histone H2B also known as Histone H2B with Anti-Histone H2B Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB & IHC.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Western blot
Immunohistochemistry on paraformaldehyde treated sections.
Optimal working dilutions must be determined by end user.
Immunohistochemistry on paraformaldehyde treated sections.
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Reacts with histone H2B in human nuclear fractions. No cross-reactivity with other histones, H1, H2A, H3 or H4. Binding of histones from other species has not been tested, but it is likely as the amino acid sequence of histone H2B has been found to be identical in all species examined.
Physical form
Rabbit antiserum. Liquid. Contains no preservative.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Other Notes
Replaces: MABE15
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Related Content
Histone H1 is released from myonuclei and present in rimmed vacuoles with DNA in inclusion body myositis.
Satoshi Nakano, Akiyo Shinde, Kengo Fujita, Hidefumi Ito, Hirofumi Kusaka, Satoshi Nakano et al.
Neuromuscular Disorders null
Ricardo Martinez-Zamudio et al.
Molecular and cellular biology, 32(13), 2490-2502 (2012-05-02)
The packaging of DNA into nucleosomes imposes obstacles on gene transcription, and histone-modifying and nucleosome-remodeling complexes work in concert to alleviate these obstacles so as to facilitate transcription. Emerging evidence shows that chromatin-associated poly(ADP-ribose) polymerase 1 (PARP-1) and its enzymatic
Daniel R Arnold et al.
Developmental biology, 313(1), 347-358 (2007-11-27)
Growing oocytes accumulate mRNAs and proteins that support early embryogenesis. Among the most abundant of these maternal factors are the histones. Histone mRNA accumulation and translation are mainly restricted to S-phase in somatic cells, and the mechanism by which oocytes
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB1623 | 04053252673955 |