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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
15
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat, human, bovine, mouse
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
bovine ... Parp1(286764)
human ... PARP1(142)
mouse ... Parp1(11545)
rat ... Parp1(25591)
Immunogen
Synthetic peptide based on the sequence from the C-terminal portion of the bovine PARP automodification domain (amino acids 509-524) conjugated to a carrier.
Application
Research Category
Apoptosis & Cancer
Metabolism
Apoptosis & Cancer
Metabolism
Research Sub Category
Apoptosis - Additional
Enzymes & Biochemistry
Apoptosis - Additional
Enzymes & Biochemistry
This Anti-PARP Poly ADP-ribose Polymerase-1 Antibody is validated for use in ELISA, WB for the detection of PARP Poly ADP-ribose Polymerase-1.
Western blot: 1:500 using alkaline phosphatase.
ELISA
Optimal working dilutions must be determined by end user.
ELISA
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Recognizes 116 kDa PARP-1 and the 85 kDa apoptosis-related cleavage fragment.
Physical form
Antiserum containing 0.05% sodium azide. Liquid containing 0.05% sodium azide.
Preparation Note
Maintain frozen at -20°C in undiluted aliquots for up to 12 months.
Other Notes
Replaces: 04-575; 04-576
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Related Content
D Lamarre et al.
Biochimica et biophysica acta, 950(2), 147-160 (1988-07-13)
Poly(ADP ribose) polymerase (EC 2.4.2.30) was studied using monoclonal antibodies for three different epitopes on the enzyme. The epitopes were mapped in relation to the functional domains of the protein and the inhibitory properties of the antibodies. The intranuclear and
Lauren K Jillson et al.
Molecular cancer research : MCR, 19(7), 1123-1136 (2021-04-14)
Prostate cancer genomic subtypes that stratify aggressive disease and inform treatment decisions at the primary stage are currently limited. Previously, we functionally validated an aggressive subtype present in 15% of prostate cancer characterized by dual deletion of MAP3K7 and CHD1.
MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells.
Brest, P; Lassalle, S; Hofman, V; Bordone, O; Gavric Tanga, V; Bonnetaud, C; Moreilhon et al.
Endocrine-Related Cancer null
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB16661 | 04053252320569 |