AB1952P
Anti-Integrin beta 1 (CD29) Antibody
CHEMICON®, rabbit polyclonal
Synonym(s):
CD29
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
human, rat, pig, mouse
Application:
IP, WB
Citations:
12
Product Name
Anti-Integrin β1 Antibody, cytosolic, Chemicon®, from rabbit
biological source
rabbit
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, rat, pig, mouse
manufacturer/tradename
Chemicon®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ITGB1(3688)
General description
130kDa
Immunogen
Epitope: cytosolic
Synthetic peptide corresponding to the C-terminus of human integrin beta 1 (a.a. CTTVVNPKYEGK)
Application
Detect Integrin β1 using this Anti-Integrin β1 Antibody, cytosolic validated for use in IP & WB.
Western blot: 1-2μg/mL for detection in whole cell lysate. The antibody is effective against reduced (MW = 130kDa) and non-reduced (MW = 110kDa) proteins.
Immunoprecipitation
Optimal working dilutions must be determined by the end user.
Immunoprecipitation
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Reactive with human, mouse, and rat integrin beta-1, as confirmed by western blot. Not reactive with other integrins.
Physical form
Format: Purified
Protein A Purified immunoglobulin. Liquid in PBS containing 0.1% sodium azide.
Analysis Note
Control
U251 cell line Skin (Basement Membrane)
U251 cell line Skin (Basement Membrane)
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Storage Class
12 - Non Combustible Liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: identification of the minimal N-glycosylation requirement for alpha5beta1.
Tomoya Isaji,Yuya Sato,Tomohiko Fukuda,Jianguo Gu
The Journal of Biological Chemistry null
Jean-Baptiste Oudart et al.
Cell adhesion & migration, 15(1), 215-223 (2021-07-27)
We previously demonstrated that F4 peptide (CNPEDCLYPVSHAHQR) from collagen XIX was able to inhibit melanoma cell migrationin vitro and cancer progression in a mouse melanoma model. The aim of the present work was to study the anti-angiogenic properties of F4 peptide. We demonstrated that F4
Xiaoming Bai et al.
Scientific reports, 4, 6538-6538 (2014-10-08)
Prostaglandin E2 (PGE2) has been implicated in cell invasion in hepatocellular carcinoma (HCC), via increased β1-integrin expression and cell migration; however, the mechanism remains unclear. PGE2 exerts its effects via four subtypes of the E prostanoid receptor (EP receptor 1-4).
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB1952P | 04053252621383 |