Anti-Monocarboxylate Transporter 4 Antibody

A 19 amino acid peptide sequence near the C-terminus of rat/human/mouse MCT4.

Detect Monocarboxylate Transporter 4 using this Anti-Monocarboxylate Transporter 4 Antibody validated for use in ELISA & WB.

Research Category
Neuroscience

Research Sub Category
Ion Channels & Transporters

Western blot: 1-5 mg/mL using ECL.



ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.

Optimal working dilutions must be determined by the end user.

Recognizes rat Monocarboxylate Transporter 4 (MCT4/MOT4/ SLC16A3). The immunogen shows no significant sequence homology with other MCT. MCT4 is prominently expressed in skeletal muscle and other cells with high glycolytic rate such as tumors cells and white blood cells suggesting an important role in lactic acid efflux.

Note: According to new nomenclature, the old MCT3 has now been reclassified as MCT4. Consult Halestrap and Price (1999) Biochem. J. 343:281-299.

SPECIES REACTIVITIES:

Rat. The immunogen sequence is 100% conserved in human and mouse and 78% conserved in chicken. Reactivity with other species has not been confirmed.

Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA and 0.05% sodium azide.

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Replaces: AB3546P

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