AB5336P
Anti-α-Synuclein (SNCA) Antibody
CHEMICON®, sheep polyclonal
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
rat, mouse, human
Application:
IHC
Citations:
7
Product Name
Anti-Synuclein α Antibody, Chemicon®, from sheep
biological source
sheep
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat, mouse, human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable (paraffin)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... SNCA(6622)
Immunogen
Synthetic peptide corresponding amino acids 108-120 of human alpha synuclein.
Application
Anti-Synuclein Antibody, α is an antibody against Synuclein for use in IH(P).
Immunohistochemistry: 1:1,000 on frozen or paraffin sections.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Physical form
Affinity purified immunoglobulin. Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any residue. Glycerol (1:1) can be added for additional stability.
Other Notes
Replaces: 04-1053
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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hcodes
pcodes
Hazard Classifications
Aquatic Chronic 3
Storage Class
11 - Combustible Solids
wgk
WGK 3
Certificates of Analysis (COA)
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Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain.
Eslamboli, A; Romero-Ramos, M; Burger, C; Bjorklund, T; Muzyczka, N; Mandel, RJ; Baker et al.
Brain null
Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct.
K A Conway, J C Rochet, R M Bieganski, P T Lansbury
Science (New York, N.Y.) null
Mohamed-Bilal Fares et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(7), E912-E921 (2016-02-04)
Lewy bodies (LBs) are intraneuronal inclusions consisting primarily of fibrillized human α-synuclein (hα-Syn) protein, which represent the major pathological hallmark of Parkinson's disease (PD). Although doubling hα-Syn expression provokes LB pathology in humans, hα-Syn overexpression does not trigger the formation
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB5336P | 04053252337574 |