AB5986P
Anti-Tyrosine Hydroxylase Antibody
CHEMICON®, rabbit polyclonal
Synonym(s):
TH, Tyrosine Monooxygenase
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
rat
Application:
IHC
Citations:
10
Product Name
Anti-Tyrosine Hydroxylase Antibody, Chemicon®, from rabbit
biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... TH(7054)
Immunogen
Synthetic peptide corresponding to amino acids 32-47 of rat Tyrosine Hydroxylase.
Application
Detect Tyrosine Hydroxylase using this Anti-Tyrosine Hydroxylase Antibody validated for use in IH.
Immunohistochemistry: 0.5-1.0 μg/mL.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neuronal & Glial Markers
Neurotransmitters & Receptors
Neuronal & Glial Markers
Biochem/physiol Actions
Tyrosine Hydroxylase. Immunohistochemical distribution throughout the brain shows that staining is restricted to those neurons known to contain the enzyme. The antibody has proven useful in staining catecholaminergic neurons. AB5986 stains these neurons intensely, including dendritic processes and fine nerve terminals.
Physical form
Affinity purified immunoglobulin.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Immunohistochemical studies on phosphorylation of tyrosine hydroxylase in central catecholamine neurons using site- and phosphorylation state-specific antibodies.
Xu, Z Q, et al.
Neuroscience, 82, 727-738 (1998)
D Rotllant et al.
Neuroscience, 168(3), 691-705 (2010-04-22)
Previous studies have shown that amphetamine (AMPH) markedly activates dopaminergic projection areas, together with some important limbic nuclei. However, a global picture of the brain areas activated is lacking and the contribution of the dose of the drug and individual
Stephanie J Cragg et al.
The European journal of neuroscience, 20(7), 1788-1802 (2004-09-24)
The direct modulation of subthalamic nucleus (STN) neurons by dopamine (DA) neurons of the substantia nigra (SN) is controversial owing to the thick caliber and low density of DA axons in the STN. The abnormal activity of the STN in
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB5986P | 04053252731365 |