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ABS538

Anti-FABP1 Antibody

serum, from rabbit

Synonym(s):

Fatty acid-binding protein, liver, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, p14

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
4
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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

species reactivity (predicted by homology)

rat (based on 100% sequence homology)

technique(s)

western blot: suitable

NCBI accession no.

NP_036688

UniProt accession no.

P02692

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

rat ... Fabp1(24360)

General description

FABP1, also known as Fatty acid-binding protein, Liver Fatty acid-binding protein, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, or p14, and encoded by the gene FABP1/FABPL, is an important fatty acid binding and transport protein. FABP1 is produced in the liver and is part of a family of lipid carrier proteins. FABP1 facilitate the transfer of fatty acids between extra and intracellular membranes. FABP1 level in the blood is used as a biomarker for obesity and type II diabetes. Additionally, recent research indicates that FABP1 can modulate stellate cell activation and this may lead to diet-induced nonalcoholic fatty liver disease, thus FABP1 is a key focus of metabolic research.
~ 14 kDa observed

Immunogen

Recombinant protein corresponding to rat FABP1.

Application

Anti-FABP1 Antibody detects level of FABP1 & has been published & validated for use in FABP1.
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected FABP1 in wild type mouse liver cytosol and not in LFABP-1 -/- mouse liver cytosol.

Analysis Note

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected FABP1 in 10 µg of human liver tissue lysate.

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Storage Class

10 - Combustible liquids

wgk

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Liver fatty acid-binding protein binds monoacylglycerol in vitro and in mouse liver cytosol.
Lagakos, William S, et al.
The Journal of Biological Chemistry, 288, 19805-19815 (2013)
William Stacy Lagakos et al.
American journal of physiology. Gastrointestinal and liver physiology, 300(5), G803-G814 (2011-02-26)
It has long been known that mammalian enterocytes coexpress two members of the fatty acid-binding protein (FABP) family, the intestinal FABP (IFABP) and the liver FABP (LFABP). Both bind long-chain fatty acids and have similar though not identical distributions in

Global Trade Item Number

SKUGTIN
ABS53804053252970108