MAB1676
Anti-Talin 1 Antibody, NT, a.a. 139-433, clone TA205
clone TA205, Chemicon®, from mouse
Synonym(s):
Anti-ILWEQ, Anti-TLN, Anti-talin-1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
TA205, monoclonal
Application:
IHC, IP, WB
Citations:
14
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
TA205, monoclonal
species reactivity
rabbit, human
should not react with
mouse, rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... TLN1(7094)
Immunogen
Epitope: N-terminus, a.a. 139-433
Application
Anti-Talin 1 Antibody, N-terminus, a.a. 139-433, clone TA205 detects level of Talin & has been published & validated for use in IP, WB, IH.
Immunoblotting, recognizes a band at ~230kDa.
Immunoprecipitation
Immunofluorescence
Optimal working dilutions must be determined by end user.
Immunoprecipitation
Immunofluorescence
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Human Talin. This antibody reacts with an N-terminal epitope in talin, between amino acids 139-433. On microinjection into whole cells MAB1676 disrupts actin stress fibers and focal contacts and inhibits cell motility.
Physical form
Format: Purified
Liquid in 0.02 M PB pH 7.6, 0.25 M NaCl containing 0.1% sodium azide.
Preparation Note
Maintain between 2 and 8°C for up to six months.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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D C Love et al.
Experimental parasitology, 88(3), 161-171 (1998-04-30)
In the present study, we examine the cell biology of Leishmania amastigote uptake by mammalian cells and compare this process to the phagocytosis of IgG-opsonized erythrocytes. We report that many aspects of amastigote uptake into macrophages resemble classical receptor-mediated phagocytosis.
Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the ?1 integrin-RACK1 axis.
Trerotola, M; Li, J; Alberti, S; Languino, LR
Journal of Cellular Physiology null
Li-Ting Su et al.
The Journal of biological chemistry, 281(16), 11260-11270 (2006-01-27)
m-Calpain is a protease implicated in the control of cell adhesion through focal adhesion disassembly. The mechanism by which the enzyme is spatially and temporally controlled is not well understood, particularly because the dependence of calpain on calcium exceeds the
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB1676 | 04053252317071 |