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MAB2168

Anti-Huntingtin Disease (HD/HTT) Antibody

CHEMICON®, mouse monoclonal, HU-2E8

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
HU-2E8, monoclonal
Species reactivity:
monkey, human
Application:
ELISA, ICC, IHC, WB
Citations:
19
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Product Name

Anti-Huntingtin Protein Antibody, a.a. 2146-2541, clone HU-2E8, ascites fluid, clone HU-2E8, Chemicon®

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

HU-2E8, monoclonal

species reactivity

monkey, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable

isotype

IgG1

NCBI accession no.

NM_002111.6

UniProt accession no.

P42858

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... HTT(3064), SLC6A4(6532)

Immunogen

Epitope: a.a. 2146-2541
Human huntingtin fragment from aa 2146 to 2541 as a fusion protein.

Application

Anti-Huntingtin Protein Antibody, a.a. 2146-2541, clone HU-2E8 is an antibody against Huntingtin Protein for use in ELISA, WB, IC, IH(P).
ELISA: 1:500-1:5,000

Western blot: 1:500-1:5,000

Immunohistochemistry on frozen and microwave oven treated paraffin sections

(human tissue): 1:500-1:5,000

Immunocytochemistry on transfected cells: 1:500-1:5,000

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Biochem/physiol Actions

Reacts with Huntingtin protein from human and monkey. Weak to no reactivity with mouse. Has not been tested on other species.

Physical form

Ascites fluid. Liquid, does not contain any preservative.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington's disease.
Paula A Desplats, James R Lambert, Elizabeth A Thomas, Paula A Desplats, James R Lambert et al.
Neurobiology of Disease null
Increased apoptosis, Huntingtin inclusions and altered differentiation in muscle cell cultures from Huntington's disease subjects.
Ciammola, A; Sassone, J; Alberti, L; Meola, G; Mancinelli, E; Russo, MA; Squitieri, F; Silani, V
Cell Death and Differentiation null
Huntingtin distribution among striatal output neurons of normal rat brain
Fusco, F.R. et al.
Neuroscience Letters, 339, 53-56 (2003)
View All Related Papers

Global Trade Item Number

SKUGTIN
MAB216804053252399664