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MAB395

Anti-Myelin Basic Protein Antibody

CHEMICON®, rat monoclonal, 14

Synonym(s):

MBP

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
14, monoclonal
Technique(s):
ELISA: suitable, immunohistochemistry: suitable
Application:
ELISA, IHC
Citations:
7
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Product Name

Anti-Myelin Basic Protein Antibody, a.a. 36-50, clone 14, culture supernatant, clone 14, Chemicon®

biological source

rat

Quality Level

100

antibody form

culture supernatant

antibody product type

primary antibodies

clone

14, monoclonal

species reactivity (predicted by homology)

mammals

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunohistochemistry: suitable

isotype

IgG2b

NCBI accession no.

NM_001025081.1, NM_001025090.1, NM_001025092.1, NM_001025094.1, NM_001025098.1, NM_001025100.1, NM_001025101.1, NM_002385.2

UniProt accession no.

P02686

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... MBP(4155)

Immunogen

Bovine myelin basic protein.
Epitope: a.a. 36-50

Application

Research Sub Category
Neuronal & Glial Markers

Neurochemistry & Neurotrophins
Detect Myelin Basic Protein using this Anti-Myelin Basic Protein Antibody, a.a. 36-50, clone 14 validated for use in ELISA, IH.
Immunohistochemistry (frozen sections)

ELISA

This antibody is also expected to work for Western blot. Specific testing has not been performed.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience

Biochem/physiol Actions

Reacts with a synthetic peptide corresponding to human MBP sequence 36-50 as well as intact human MBP. Numbering of MBP residues is as described by Martenson (1984). Mapped by Geyson method to FFGGDR and RFFGGO region.

Physical form

Tissue culture supernatant. Liquid containing 0.09% sodium azide.

Preparation Note

Maintain at -20° in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze-thaw cycles.

Other Notes

Replaces: MAB395

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mild hypothermia ameliorates anesthesia toxicity in the neonatal macaque brain.
Ikonomidou, et al.
Neurobiology of Disease, 130, 104489-104489 (2020)
Anzari Atik et al.
Frontiers in physiology, 10, 990-990 (2019-08-21)
Caffeine is one of the few treatments available for infants with apnea of prematurity. As the recommended dosing regimen is not always sufficient to prevent apnea, higher doses may be prescribed. However, little is currently known about the impact of
Feng Mei et al.
Nature medicine, 20(8), 954-960 (2014-07-07)
Functional screening for compounds that promote remyelination represents a major hurdle in the development of rational therapeutics for multiple sclerosis. Screening for remyelination is problematic, as myelination requires the presence of axons. Standard methods do not resolve cell-autonomous effects and
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Global Trade Item Number

SKUGTIN
MAB395-1ML04053252662676