Skip to Content
Merck
CN

Key Documents

View All Documentation

MKI1MAG-94K

MILLIPLEX® Mouse Kidney Injury Panel

Configurable Mouse Kidney Injury 6-Plex Panel 1

Synonym(s):

kidney inflammation marker listing, mouse kidney biomarker panel, mouse kidney disease assay, mouse renal damage detection panel, multiplex kidney profiling kit, nephrotoxicity assay overview, renal function biomarker panel, renal injury multiplex kit

Sign In to View Organizational & Contract Pricing.

About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Product Name

MILLIPLEX® Mouse Kidney Injury Panel, Configurable Mouse Kidney Injury 6-Plex Panel 1

Quality Level

200

species reactivity

mouse

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 73-98%, sensitivity: 0.001-0.041 ng/mL
(MinDC+2SD), standard curve range: 0.001-1 ng/mL
(VEGF), standard curve range: 0.005-5 ng/mL
(IP-10), standard curve range: 0.01-15 ng/mL
(KIM-1), standard curve range: 0.02-25 ng/mL
(TIMP-1), standard curve range: 0.05-50 ng/mL
(β-2-Microglobulin), standard curve range: 0.05-50 ng/mL
(Renin)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Kidney injury can result from various factors including drug toxicity, hypertension, and metabolic disorders. Traditional markers like BUN and creatinine are often insensitive and non-specific. This panel—β-2-Microglobulin, IP-10/CXCL10, KIM-1, Renin, TIMP-1, and VEGF-A—captures key indicators of renal damage, inflammation, and vascular response. The MILLIPLEX® Mouse Kidney Injury Panel 1 enables multiplexed quantification of these biomarkers in mouse urine, serum, or plasma, supporting research in nephrotoxicity, renal disease, and therapeutic development.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 6 analytes in mouse urine, serum, or plasma samples.

Analytes Included: β-2-Microglobulin, IP-10/CXCL10, KIM-1, Renin, TIMP-1, VEGF-A Note: β-2-Microglobulin and VEGF-A are to be measured in urine samples only.

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:
  • Targets biomarkers involved in renal injury, inflammation, and vascular regulation
  • Includes 6 analytes relevant to nephrotoxicity and kidney function assessment
  • Multiplex format enables simultaneous detection from minimal sample volume Compatible with mouse urine, serum, and plasma samples
  • Designed for research in acute kidney injury, drug-induced nephrotoxicity, and renal disease models
Benefits:
  • Provides a focused profile of kidney injury biomarkers in mouse models
  • Supports investigation of renal damage mechanisms and therapeutic evaluation
  • Facilitates early detection of nephrotoxicity and disease progression
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for preclinical and translational research

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Still not finding the right product?

Explore all of our products under MILLIPLEX® Mouse Kidney Injury Panel

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Regulatory Information

新产品

This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Related Content

Overview of Luminex® Multiplex Assay Technology | MILLIPLEX® Multiplex Assays

Discover the benefits of MILLIPLEX® multiplex assays, based on Luminex® xMAP® multiplex assay technology, that provide consistent, high-quality results and see how these multiplex biomarker Luminex® assays are being used to advance research.

Multiplex Toxicity Assays | MILLIPLEX® Assays

Multiplex toxicity assays enable researchers to simultaneously measure multiple toxicity biomarkers of various organs to gain a better understanding of toxicity. Explore how MILLIPLEX® multiplex toxicity assays are advancing research on liver injury, kidney toxicity, genotoxicity, and more.

Nephrotoxicity Analysis with Kidney Toxicity Multiplex Assays | MILLIPLEX® Assays

Novel kidney toxicity biomarkers expand options for acute nephrotoxicity detection. Multiplex assays measure multiple renal damage biomarkers in small sample volumes, minimizing time and costs. See how MILLIPLEX® multiplex kidney toxicity assays detected vancomycin-induced subacute nephrotoxicity in rat models.

View All Related Content
Gene Ryan Crislip et al.
Biomolecules, 12(2) (2022-02-26)
BMAL1 is a core mammalian circadian clock transcription factor responsible for the regulation of the expression of thousands of genes. Previously, male skeletal-muscle-specific BMAL1-inducible-knockout (iMS-BMAL1 KO) mice have been described as a model that exhibits an aging-like phenotype with an
Monica Javidnia et al.
Journal of Alzheimer's disease : JAD, 60(2), 461-481 (2017-09-05)
Hyperphosphorylation and aggregation of tau protein is a critical factor in many neurodegenerative diseases. These diseases are increasing in prevalence, and there are currently no cures. Previous work from our group and others has shown that tyrosine kinase inhibitors (TKIs)

Global Trade Item Number

SKUGTIN
MKI1MAG-94K04055977114683