Samplicity^® Filtration System, Bold Blue

HPLC sample prep doesn’t have to be inefficient or painful. The ideal sample prep system for most chromatographers. If you’re using chromatography to analyze dozens of pharmaceutical samples, food and beverage products or cosmetic formulations a day, especially hard-to-filter, viscous or particulate-laden samples, you know that traditional filtration methods can result in: Slow filtration speed/clogging, Filter bursting or spillage, Sample volume loss (most undesirable for small-volume samples), and Operator fatigue. The first vacuum-driven system with the flexibility to filter 1 to 8 samples directly into standard HPLC sample vials, the Samplicity® Filtration System addresses all of the challenges facing analytical chromatographers. Just attach a vacuum pump, load your samples, and flip the lever. Recover your particulate-free samples in seconds.

In this application note, we present data showing that the Samplicity® system can be used for filtration of smaller volume samples into HPLC vials containing inserts. Syringe filters prove less efficient for users typically filtering 10 – 100 samples a day (65 – 70% of users). For these users, the Samplicity® multifiltration system facilitates sample preparation by enabling vacuum-driven filtration of up to eight samples directly into standard (12 x 32 mm) HPLC vials. The Samplicity® system has been used widely to filter 300 μL – 2 mL samples into HPLC vials without inserts.

The Samplicity™ filtration system has helped researchers streamline chromatographic sample preparation in order to match the speed and throughput requirements of their analytical separations such as high/ultrahigh performance liquid chromatography (HPLC /UHPLC). An easy-to-use alternative to syringe filters, the Samplicity™ system enables simultaneous vacuum filtration of up to eight samples. Even difficult-to-filter samples with high viscosity or particulates can be processed in seconds. Our data show that the Samplicity™ system facilitates preparation of chromatography samples with high recovery, low extractables and very low passage of particulate impurities.