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Merck
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10102121001

Roche

Adenosine Deaminase (ADA)

from calf intestine

Synonym(s):

ADA, Adenosine Deaminase

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About This Item

UNSPSC Code:
12352204
EC Number:
NACRES:
NA.54
Specific activity:
~200 units/mg protein (At 25 °C with adenosine as the substrate.)
Biological source:
bovine intestine
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biological source

bovine intestine

form

suspension

specific activity

~200 units/mg protein (At 25 °C with adenosine as the substrate.)

packaging

pkg of 1 mL (10 mg)

manufacturer/tradename

Roche

technique(s)

activity assay: suitable

color

white

optimum pH

7.0-7.4

solubility

water: miscible

suitability

suitable for chemiluminescence

NCBI accession no.

UniProt accession no.

application(s)

life science and biopharma

foreign activity

AMP-deaminase <0.01%, AP <0.01% (with pre incubation), Guanase <0.01%, NP <0.01%

storage temp.

2-8°C

Gene Information

bovine ... ADA(280712)

General description

Adenosine aminohydrolase.
Adenosine deaminase (ADA) is a zinc metalloenzyme.

Application

Chemiluminescent adenosine assay.
Deamination of adenosine analogs to the corresponding inosine analogs
Adenosine deaminase (ADA) has been used in lipolysis assay along with other reagents.

Biochem/physiol Actions

Adenosine deaminase (ADA) is involved in the deamination of adenosine to inosine and 2′ deoxyadenosine to 2′-deoxyinosine.

Physical form

Suspension in 3.2 M ammonium sulfate solution, pH approximately 6. Small particles are normal. Before using stir up the precipitate and proceed.

Analysis Note

Contaminants: <0.01% alkaline phosphatase, AMP-deaminase, guanase, and nucleoside phosphorylase each

Other Notes

For life science research only. Not for use in diagnostic procedures.


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

No data available

flash_point_c

No data available

Regulatory Information

动植物源性产品
低风险生物材料

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Cultured astrocytes do not release adenosine during hypoxic conditions.
Fujita T, et al.
Journal of Cerebral Blood Flow and Metabolism, 32(1), e1-e7 (2012)
Adenosine deaminase from calf intestinal mucosa.
C A ZITTLE
The Journal of biological chemistry, 166(2), 499-503 (1946-12-01)
Sonia Muñoz-López et al.
Frontiers in endocrinology, 13, 1007801-1007801 (2022-11-22)
Despite great efforts, effective treatment against cancer has not yet been found. However, natural compounds such as the polyphenol resveratrol have emerged as promising preventive agent in cancer therapy. The mode of action of resveratrol is still poorly understood, but



Global Trade Item Number

SKUGTIN
1010212100104061838665478