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10108294001

Roche

Phosphoenol-pyruvate

97% (PEP-K), pkg of 1 g

Synonym(s):

Phospho(enol)pyruvic acid monopotassium salt, 2-(Phosphonooxy)-2-propenoic acid monopotassium salt, mono-Potassium phosphoenolpyruvate, PEP-K

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About This Item

Empirical Formula (Hill Notation):
C3H4KO6P
CAS Number:
4265-07-0
Molecular Weight:
206.13
PubChem Substance ID:
329748896
UNSPSC Code:
12352204
Beilstein/REAXYS Number:
4603446
MDL number:
MFCD00044476
NACRES:
NA.54
Assay:
97% (PEP-K)
Form:
solid
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description

C3H4O6PK (Formula), PEP, monopotassium salt

assay

97% (PEP-K)

form

solid

mol wt

Mr 168.0 (PEP), Mr 206.1 (PEP-K)

packaging

pkg of 1 g

manufacturer/tradename

Roche

storage temp.

2-8°C

SMILES string

[K+].OC(=O)C(=C)OP(O)([O-])=O

InChI

1S/C3H5O6P.K/c1-2(3(4)5)9-10(6,7)8;/h1H2,(H,4,5)(H2,6,7,8);/q;+1/p-1

InChI key

SOSDSEAIODNVPX-UHFFFAOYSA-M

General description

Contents: 80% PEP (enzymatic)

Application

Phosphoenolpyruvate (PEP) has been used in:
  • glutamate-cysteine ligase activity
  • v-ATPase enzyme activity assay
  • meso kinase assay

Substrate for pyruvate kinase.

Biochem/physiol Actions

Phosphoenolpyruvate (PEP) plays a vital role in metabolism. It has a high phosphate group-transfer potential and it serves a versatile C3-synthon in C–C, C–P and C–O bond-formation reactions. PEP acts as a substrate for pyruvate kinase (PK) in the last step of glycolysis.

Other Notes

For life science research only. Not for use in diagnostic procedures.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
13516338
13516347
13516345
13516342
90086820

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Synthesis of phosphoenol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes.
Garcia A, et al.
FEBS Journal, 269(13), 3226-3236 (2002)
Glutathione participates in the modulation of starvation-induced autophagy in carcinoma cells.
Desideri E
Autophagy, 8(12), 1769-1781 (2012)
Maria B Bagh et al.
Nature communications, 8, 14612-14612 (2017-03-08)
Defective lysosomal acidification contributes to virtually all lysosomal storage disorders (LSDs) and to common neurodegenerative diseases like Alzheimer's and Parkinson's. Despite its fundamental importance, the mechanism(s) underlying this defect remains unclear. The v-ATPase, a multisubunit protein complex composed of cytosolic
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Global Trade Item Number

SKUGTIN
1010829400104061838666932