Ethylenediaminetetraacetic acid tetrasodium salt hydrate

Name: Ethylenediaminetetraacetic acid tetrasodium salt hydrate
Brand: SIAL

≥97.0% (KT)

Synonym(s):

Tetrasodium EDTA, EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate hydrate

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About This Item

Linear Formula:

(NaOOCCH₂)₂NCH₂CH₂N(CH₂COONa)₂ · xH₂O

CAS Number:

194491-31-1

Molecular Weight:

380.17 (anhydrous basis)

UNSPSC Code:

12352116

NACRES:

NA.22

PubChem Substance ID:

329747782

EC Number:

200-573-9

Beilstein/REAXYS Number:

3861753

MDL number:

MFCD00150025

Assay:

≥97.0% (KT)

Form:

powder

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Properties

Quality Level

200

assay

≥97.0% (KT)

form

powder

functional group

amine

InChI

1S/C10H16N2O8.4Na.H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;1H2/q;4*+1;/p-4

InChI key

GXFFSKMBMYHTAE-UHFFFAOYSA-J

Description

Application

EDTA is an inhibitor of metalloproteases, at effective concentrations of 1-10 mM. EDTA acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. The optimal concentration is 1.5 mg per ml of blood.

Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.