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12279

1,2-Propanediol

analytical standard

Synonym(s):

1,2-PDO, Propylene glycol

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About This Item

Linear Formula:
CH3CH(OH)CH2OH
CAS Number:
57-55-6
Molecular Weight:
76.09
NACRES:
NA.24
E Number:
E490
PubChem Substance ID:
329749683
UNSPSC Code:
41116107
EC Number:
200-338-0
MDL number:
MFCD00064272
Beilstein/REAXYS Number:
1340498
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grade

analytical standard

Quality Level

100

vapor density

2.62 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

assay

≥99.7% (GC)

autoignition temp.

779 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

12.5 %

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.432 (lit.), n20/D 1.433

bp

187 °C (lit.)

mp

−60 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

format

neat

SMILES string

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

General description

1,2-Propanediol is a compound found to be chemically similar to ethylene glycol and is widely used in automobile antifreeze, activated charcoal preparations, cosmetics, beverages, ointments, etc. It is used as a diluent for the intravenous preparations of poorly water-soluble drugs.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food.

Find all available reference materials for compounds listed in 10/2011 here

Application

1,2-Propanediol may be used as an analyte protectant for the gas chromatography-mass spectrometric detection of environmental contaminants in honey, honeybees and pollens. It is also used as an analytical reference standard for the quantification of the analyte in biological fluids using headspace-gas chromatography (HS-GC) technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

217.4 °F - closed cup

flash_point_c

103 °C - closed cup

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG1547
BCCD4634
BCCB9580
BCCB3760
BCBW9031

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Protocols

利用 Nukol™ 对乙二醇类进行气相色谱分析

99%；甘油，≥99.5%；四甘醇，99%

R S Rajasenan et al.
Toxicology and applied pharmacology, 135(1), 89-99 (1995-11-01)
Engrafting components of human immune systems in severe combined immunodeficient (SCID) mice has been utilized to investigate the pathogenesis of several human autoimmune diseases and may provide a model for studying idiosyncratic drug toxicity. The purpose of this investigation was
G A Reichard et al.
Diabetes, 35(6), 668-674 (1986-06-01)
Plasma acetone turnover rates were measured with the primed continuous infusion of 2-[14C]acetone in patients with moderate to severe diabetic ketoacidosis. Plasma acetone turnover rates ranged from 1.52 to 15.9 mumol X kg-1 X min-1 (108-1038 mumol X 1.73 m-2
H K Vaddi et al.
Journal of pharmaceutical sciences, 91(7), 1639-1651 (2002-07-13)
The respective alcoholic terpenes carvacrol, linalool, and alpha-terpineol were used at 5% w/v in propylene glycol (PG) to increase the in vitro permeation of haloperidol (HP) through human skin. The possible enhancement mechanism was then elucidated with HP-stratum corneum (SC)
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Global Trade Item Number

SKUGTIN
12279-1ML-F04061838721778
12279-5ML-F04061838721785