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15522

D-(+)-Galactose

meets analytical specification of Ph. Eur., BP

Synonym(s):

Galactose

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
59-23-4
Molecular Weight:
180.16
UNSPSC Code:
12352201
NACRES:
NA.21
PubChem Substance ID:
57647466
EC Number:
200-416-4
Beilstein/REAXYS Number:
1724619
MDL number:
MFCD00151230
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form

powder

Quality Level

200

quality

meets analytical specification of Ph. Eur., BP

technique(s)

IR spectroscopy: suitable

impurities

acid. or alk. react. impurities, in accordance, microbiological impurity, in accordance, residual solvents, in accordance, ≤1.0% water (Karl Fischer)

color

white

useful pH range

5.0-7.0 (25 °C, 180 g/L)

mp

168-170 °C (lit.)

solubility

H2O: soluble 180 g/L at 20 °C

suitability

in accordance for appearance of solution, in accordance for identity (IR)

application(s)

pharmaceutical (small molecule)

SMILES string

OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6-/m0/s1

InChI key

GZCGUPFRVQAUEE-KCDKBNATSA-N

Application

D-(+)-Galactose was used for examining the specificity of staining with SBA-FITC during labeling of cells for fluorescence-activated cell sorting (FACS). It was used for selecting the transformed strains of S. cerevisiae.

Biochem/physiol Actions

Galactose is a monosaccharide sugar and is the natural antigen present on the blood cells. It induces memory loss, neurodegeneration as well as oxidative damage in mice due to systemic exposure.
Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG8311
BCCF3056
BCCD1181
BCBS5475
BCBN1941

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Elizabeth M Prescott et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(13), 8796-8801 (2002-06-22)
Transcriptional interference between genes and the regulatory elements of simple eukaryotes such as Saccharomyces cerevisiae is an unavoidable consequence of their compressed genetic arrangement. We have shown previously that with the tandem arranged genes GAL10 and GAL7, inefficient transcriptional termination
Xu Cui et al.
Journal of neuroscience research, 84(3), 647-654 (2006-05-20)
Chronic systemic exposure of mice, rats, and Drosophila to D-galactose causes the acceleration of senescence and has been used as an aging model. The underlying mechanism is yet unclear. To investigate the mechanisms of neurodegeneration in this model, we studied
P J Simmons et al.
Blood, 78(11), 2848-2853 (1991-12-01)
Normal bone marrow cells were isolated by fluorescence-activated cell sorting (FACS) on the basis of CD34 antigen expression and then assayed in vitro for colonies of fibroblastic cells (fibroblast colony-forming units [CFU-F]). Greater than 95% of detectable CFU-F were recovered
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Global Trade Item Number

SKUGTIN
N7632-500MG04061837841248
N7632-1G04061834118114
15522-100G-R04061833380505
15522-250G-R04061833440018