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158127

Paraformaldehyde

95%, powder

Synonym(s):

Polyoxymethylene

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About This Item

Linear Formula:
HO(CH2O)nH
CAS Number:
30525-89-4
Molecular Weight:
30.03 (as monomer)
UNSPSC Code:
12352100
PubChem Substance ID:
24849719
NACRES:
NA.21
MDL number:
MFCD00133991
Assay:
95%
Form:
powder
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Product Name

Paraformaldehyde, powder, 95%

vapor density

1.03 (vs air)

Quality Level

200

vapor pressure

<1.45 mmHg ( 25 °C)

assay

95%

form

powder

autoignition temp.

572 °F

expl. lim.

73 %

mp

120-170 °C (lit.)

density

0.88 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

[O-]#[C+H2]

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

General description

Paraformaldehyde is also referred as polyoxymethylene. It participates as an external CO source in the synthesis of aromatic aldehydes and esters.

Application

Paraformaldehyde can be used as a:
  • Methylene building block in the Mannich reaction with primary amines and alkynes to synthesize propargyl amines.
  • Hydroxymethylation reagent to synthesize homoallylic alcohols by reacting with 1,1-disubstituted allenes.
  • Formylation reagent in the Ir-catalyzed N-formylation of amines to synthesize formamides.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Flam. Sol. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品

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Certificates of Analysis (COA)

Lot/Batch Number
STBK7046
STBK5668
STBK5667
STBK4638
STBK4639

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Protocols

蛋白相互作用

本协议描述了一种使用甲醛完成化学交联蛋白质的方法。除零长交联剂外，甲醛是交联跨度最短（~2-3 Å）的交联剂，因此使其成为非常可靠地检测特定蛋白质-蛋白质相互作用的理想工具。

Protein Interactions

Formaldehyde cross-linking protocol detects specific protein interactions with confidence.

Morphological and physiological species-dependent characteristics of the rodent Grueneberg ganglion
Brechbuhl J, et al.
Frontiers in Neuroanatomy, 8, 87-87 (2014)
Flow acetone-staining technique: A highly efficient procedure for the simultaneous analysis of DNA content, cell morphology, and immunophenotype by flow cytometry
Carbonari M, et al.
Cytometry. Part A : the Journal of the International Society For Analytical Cytology, 73(2), 168-174 (2008)
In Situ Hybridization in Neurobiology, 27-27 (1994)
View All Related Papers

Global Trade Item Number

SKUGTIN
158127-100G04061835320288
158127-3KG04061835320295
158127-500G04061835320301
158127-5G04061835320318