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31586

Amoxicillin trihydrate

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C16H19N3O5S · 3H2O
CAS Number:
61336-70-7
Molecular Weight:
419.45
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329753834
MDL number:
MFCD00072029
Beilstein/REAXYS Number:
7507120
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grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(O)=O

InChI

1S/C16H19N3O5S.3H2O/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;;;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);3*1H2/t9-,10-,11+,14-;;;/m1.../s1

InChI key

MQXQVCLAUDMCEF-CWLIKTDRSA-N

General description

Amoxicillin trihydrate is a β-lactam antibiotic. It is a broad-spectrum drug mostly administered orally.1 It is used to treat bacterial infections mainly caused by susceptible microorganisms.2
Chemical structure: β-lactam

Application

Amoxicillin trihydrate may be used as reference standard in stability study of Amoxicillin-Clavulanate in BACTEC Medium performed using HPLC.3
Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

涉药品监管产品

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Certificates of Analysis (COA)

Lot/Batch Number
BCCD7558
BCCB7876
BCCB1309

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Claudia Foti et al.
Molecules (Basel, Switzerland), 25(14) (2020-07-12)
A potentiometric and UV spectrophotometric investigation on Mn2+-ampicillin and Mn2+-amoxicillin systems in NaCl aqueous solution is reported. The potentiometric measurements were carried out under different conditions of temperature (15 ≤ t/°C ≤ 37). The obtained speciation pattern includes two species
Qian Zhao et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 67(7), 1605-1611 (2013-04-05)
This paper investigated the effects of selected common chemical species in natural waters (HCO3(-), NO3(-) and humic acids (HA)) on the photodegradation of amoxicillin (AMO) under simulated irradiation using a 300 W xenon lamp. Quenching experiments were carried out to
Enrique Gómez et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 110(4), 267-273 (2013-03-29)
Although allergic drug reactions have been considered to be immediate (IgE mediated) or delayed (T-cell effector mechanisms), accelerated reactions have also been defined; however, they have not been sufficiently studied. To study the mechanisms involved in accelerated reactions to amoxicillin.
View All Related Papers

Global Trade Item Number

SKUGTIN
31586-250MG04061835515011