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Merck
CN

33247

Urea

ACS reagent grade, ≥99%, solid, puriss. p.a., reag. Ph. Eur.

Synonym(s):

Carbamide, Carbonyldiamide

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About This Item

Linear Formula:
NH2CONH2
CAS Number:
Molecular Weight:
60.06
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-315-5
MDL number:
Beilstein/REAXYS Number:
635724
Assay:
≥99%, 99-101% (calc. on dry substance)
Form:
solid
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Product Name

Urea, puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99%

Quality Level

agency

reag. Ph. Eur.

grade

ACS reagent, puriss. p.a.

assay

≥99%, 99-101% (calc. on dry substance)

form

solid

impurities

alkalic reac. substances, complies, ≤0.0005% heavy metals (as Pb), ≤0.05% ammonium (NH4), ≤0.1% biuret

ign. residue

≤0.01% (as SO4)

loss

≤1.0% loss on drying, 105°C, 1 h

mp

132-135 °C

solubility

H2O: soluble 480 g/L at 20 °C

density

1.335 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤5 mg/kg, sulfate (SO42-): ≤10 mg/kg

cation traces

Fe: ≤2 mg/kg

suitability

in accordance for appearance of solution, in accordance for identity

functional group

amine

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

Gene Information

human ... CA1(759), CA2(760)
rat ... Ppm1a(24666)

General description

Urea is a colorless, odorless solid. It has prism-like crystals. It forms insoluble nitrate salts with nitric acid and oxalate salts with oxalic acid. On reaction with alkanes or substituted alkanes, it affords crystal-lattice inclusion compounds.
Urea is the most commonly used slow release nitrogen fertilizer.

Application

Urea has been used in the following studies:
  • Synthesis of SnO2 nanoparticles.
  • Synthesis of urethanes, ureides and semicarbazides.
  • Denaturation of protein isolated from Saccharomyces cerevisiae Y15696 strain.
  • Protein electrophoretic studies.
Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.


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wgk

WGK 1

flash_point_f

Not applicable

Storage Class

11 - Combustible Solids

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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The Fertilizer Encyclopedia, 709-709 (2009)
Genna L Andrews et al.
Analytical chemistry, 83(13), 5442-5446 (2011-05-31)
The TripleTOF 5600 System, a hybrid quadrupole time-of-flight mass spectrometer, was evaluated to explore the key figures of merit in generating peptide and protein identifications that included spectral acquisition rates, data quality, proteome coverage, and biological depth. Employing a Saccharomyces
Joost P J J Hegmans et al.
The American journal of pathology, 164(5), 1807-1815 (2004-04-28)
Exosomes are small membrane vesicles secreted into the extracellular compartment by exocytosis. Tumor exosomes may be involved in the sampling of antigens to antigen presenting cells or as decoys allowing the tumor to escape immune-directed destruction. The proteins present in



Global Trade Item Number

SKUGTIN
33247-2.5KG04061832977560
33247-5KG04061826736760
33247-1KG04061835365654
33247-250G04061826736753