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Merck
CN

33510

1,10-Phenanthroline monohydrate

redox indicator, ACS reagent, puriss. p.a., ≥99.5% (calc. to the dried substance)

Synonym(s):

o-Phenanthroline monohydrate

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About This Item

Empirical Formula (Hill Notation):
C12H8N2 · H2O
CAS Number:
Molecular Weight:
198.22
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-629-2
MDL number:
Beilstein/REAXYS Number:
4008096
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Product Name

1,10-Phenanthroline monohydrate, ACS reagent, puriss. p.a., ≥99.5% (calc. to the dried substance), for redox titration

Quality Level

grade

ACS reagent, puriss. p.a.

assay

≥99.5% (calc. to the dried substance), 8.5-9.5% water basis

technique(s)

titration: suitable

impurities

8.5-9.5% water

ign. residue

≤0.05% (as SO4)

mp

100-104 °C (lit.), 97-102 °C

suitability

passes test for iron detection, passes test for redox indicator

SMILES string

O.c1cnc2c(c1)ccc3cccnc23

InChI

1S/C12H8N2.H2O/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;/h1-8H;1H2

InChI key

PPQJCISYYXZCAE-UHFFFAOYSA-N

General description

1,10-Phenanthroline monohydrate is the hydrated form of o-phenanthroline.

Application

1,10-Phenanthroline monohydrate (phen) may be used in the photochemical quantification of Fe3+ and total iron in mineral samples. It may be used as starting reagent for the preparation of 5-nitro-1,10-phenanthroline.
When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.

Biochem/physiol Actions

Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.


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pictograms

Skull and crossbonesEnvironment

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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The quantitative assay of minerals for Fe2+ and Fe3+ using 1, 10-phenanthroline: II. A photochemical method.
Stucki JW.
Soil Science Society of America Journal. Soil Science Society of America, 45(3), 638-641 (1981)
Unmesh Jadhav et al.
Molecular cell, 78(1), 141-151 (2020-02-07)
Polycomb repressive complex 2 (PRC2) places H3K27me3 at developmental genes and is causally implicated in keeping bivalent genes silent. It is unclear if that silence requires minimum H3K27me3 levels and how the mark transmits faithfully across mammalian somatic cell generations.
A luminescent tris (2-thenoyltrifluoroacetonato) europium (III) complex covalently linked to a 1, 10-phenanthroline-functionalised sol-gel glass.
Binnemans K, et al.
Journal of Materials Chemistry, 14(2), 191-195 (2004)



Global Trade Item Number

SKUGTIN
33510-5G04061826738894
33510-25G04061835365678