33528
4-Aminoantipyrine
≥99%, puriss. p.a., reag. Ph. Eur.
Synonym(s):
4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, Ampyrone
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About This Item
Empirical Formula (Hill Notation):
C11H13N3O
CAS Number:
Molecular Weight:
203.24
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
201-452-3
MDL number:
Beilstein/REAXYS Number:
181635
Assay:
≥99%
Product Name
4-Aminoantipyrine, puriss. p.a., reag. Ph. Eur., ≥99%
Quality Level
agency
USP/NF, reag. Ph. Eur.
grade
puriss. p.a.
assay
≥99%
ign. residue
≤0.1%
loss
≤0.5% loss on drying
mp
105-110 °C (lit.), 107-109 °C
SMILES string
CN1N(c2ccccc2)C(=O)C(N)=C1C
InChI
1S/C11H13N3O/c1-8-10(12)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,12H2,1-2H3
InChI key
RLFWWDJHLFCNIJ-UHFFFAOYSA-N
General description
4-Aminoantipyrine forms heterocyclic Schiff bases, by reaction with various aldehydes and oximes. These Schiff bases form stable complexes with transition metals.
Application
- Phenol impurity and wastewater analysis: Research demonstrated the application of 4-Aminoantipyrine in spectrophotometric determination of phenol impurities in phenoxyethanol and for assessing phenol index in drinking water and municipal wastewater, utilizing salting-out assisted liquid phase microextraction (Roustaei et al., 2024).
- Advanced sensor development for tea polyphenols: Utilization of 4-Aminoantipyrine in developing a novel hybrid sensor array, integrated with polyphenol oxidase and its nanozymes, aided by machine learning to identify tea polyphenols and Chinese teas, showcasing its role in innovative sensor technology (Yang et al., 2024).
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Hazard Classifications
Acute Tox. 4 Oral
signalword
Warning
hcodes
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Lucas de Melo da Silva et al.
The Science of the total environment, 631-632, 1079-1088 (2018-05-08)
Electro-oxidation with electrogenerated H2O2 (EO-H2O2) was applied to treat acidic aqueous solutions of 4-aminoantipyrine (4-AA), a persistent drug metabolite of dipyrone, in sulfate medium. Trials were made using a boron-doped diamond anode in the presence of H2O2 electrogenerated on site.
Transition metal complexes with Schiff-base ligands: 4-aminoantipyrine based derivatives-a review.
Raman N, et al.
Journal of Coordination Chemistry, 62(5, 691-709 (2009)
Tao Sun et al.
Frontiers in bioengineering and biotechnology, 8, 237-237 (2020-04-09)
Hypoxia not only alters tumor microenvironment but leads to the tumor progression and metastasis as well as drug resistance. As a promising strategy, photodynamic therapy (PDT) can inhibit tumor by catalyzing O2 to cytotoxic reactive oxygen species. However, its effects
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 33528-25G-R | 04061826739754 |
| 33528-100G-R | 04061826739730 |