33818
5-Hydroxythiabendazole
PESTANAL®, analytical standard
Synonym(s):
2-(4-Thiazolyl)-5-benzimidazolol, 5-Hydroxy-2-(4-thiazolyl)benzimidazole
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About This Item
Empirical Formula (Hill Notation):
C10H7N3OS
CAS Number:
Molecular Weight:
217.25
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
analytical standard
Quality Level
product line
PESTANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
agriculture
environmental
forensics and toxicology
veterinary
format
neat
SMILES string
Oc1ccc2[nH]c(nc2c1)-c3cscn3
InChI
1S/C10H7N3OS/c14-6-1-2-7-8(3-6)13-10(12-7)9-4-15-5-11-9/h1-5,14H,(H,12,13)
InChI key
VNENJHUOPQAPAT-UHFFFAOYSA-N
General description
5-Hydroxythiabendazole present in excreta, eggs, edible tissues and milk is found to be the major metabolite of thiabendazole, an active ingredient in fungicidal preparations effective for plants. It can also be used as an anthelmintic drug, which is applicable both for humans and animals.
Application
Thiabendazole and its metabolite 5-hydroxythiabendazole can undergo specific binding with monoclonal antibodies and can further undergo immobilization on agarose gels, which can find applications in immunoaffinity chromatography.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Metabolism of thiabendazole in laying hen and lactating goats
Chukwudebe.CA, et al.
Journal of Agricultural and Food Chemistry, 42, 2964-2969 (1994)
M T Watts et al.
Journal of chromatography, 230(1), 79-86 (1982-06-11)
We have developed a rapid, sensitive and precise high-performance liquid chromatographic method using fluorescence detection for the simultaneous determination of thiabendazole and unconjugated 5-hydroxythiabendazole in serum. Sample pretreatment consists only of protein precipitation with acetonitrile containing the internal standard, 2-methylindole.
Concentrations of thiabendazole and parasite-specific IgG antibodies in the cerebrospinal fluid of a patient with disseminated strongyloidiasis.
J C Arroyo et al.
The Journal of infectious diseases, 156(3), 520-523 (1987-09-01)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 33818-10MG | 04061826744369 |