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Merck
CN

43412

(+)-Catechin

analytical standard

Synonym(s):

(+)-Cyanidanol, D-Catechin

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About This Item

Empirical Formula (Hill Notation):
C15H14O6
CAS Number:
Molecular Weight:
290.27
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
EC Number:
205-825-1
MDL number:
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grade

analytical standard

Quality Level

assay

≥99.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m0/s1

InChI key

PFTAWBLQPZVEMU-DZGCQCFKSA-N

General description

(+)-Catechin is the enantiomer of the polyphenolic flavonoid, catechin. Known for its antioxidative nature, it is present in various herbs, vegetables, fruits, green teas, chocolates, and red wines.

Application

This analytical standard can also be used as follows:
  • Method development for the multi-determination of catechin and its diastereomers in the leaf extracts and infusions obtained from five Byrsonima species using high-performance liquid chromatography, combined with photodiode array (PAD) and circular dichroism (CD) detectors
  • Determination of catechin in commercial green and black tea samples using magnetic solid phase extraction (MSPE) based on a novel adsorbent— O-carboxymethyl-chitosan-g- acrylic acid sodium salt (O-CMCs-g-AAS) copolymer deposited on magnetic graphene oxide (MGO), for sample pre-treatment and gas chromatography-mass spectrometry (GC-MS)
  • Multi-residue analysis of eight catechins and four theaflavins in three different commercial tea infusions (green, black, and oolong) by ultra high-performance liquid chromatography in combination with triple-quadrupole tandem mass spectrometry (UHPLC-MS-MS)
  • Simultaneous detection and quantification of four phenolic compounds— catechin, caffeic acid, rutin, and trans-cinnamic acid, using ultrasonic-assisted extraction and HPLC coupled with diode array detection from Physalis angulata L. plant material samples
  • Multi-residue determination of catechins, caffeine, and polyphenols, from 45 fresh Jukro tea leaf samples, collected at 40, 60, and 90-day intervals, by an HPLC-based method combined with PDA detection

Packaging

Bottomless glass bottle. Content inside is inserted in a fused cone.


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Protocols

Protocol for HPLC Analysis of Flavonoids on Ascentis® RP-Amide

HPLC Analysis of Polyphenols in Nero d'Avola Red Wine on Discovery® HS C18 (UV 280 nm)

Articles

Validated HPLC method (based on Ph. Eur. Monograph 2668) for quantifying catechins and caffeine in decaffeinated green tea using a Chromolith® High Resolution RP-18e column with advantages in terms of backpressure and matrix robustness.


Catechin contents of foods commonly consumed in The Netherlands. 1. Fruits, vegetables, staple foods, and processed foods
Arts.W.C.I, et al.
Journal of Agricultural and Food Chemistry, 48(5), 1746-1751 (2000)
Antioxidant effectiveness of selected wines in comparison with (+)-catechin
Katalinic. V, et al.
Food Chemistry, 86, 593-600 (2004)
Meran Keshawa Ediriweera et al.
Medicines (Basel, Switzerland), 4(3) (2017-09-21)
Obesity is considered as one of the risk factors for breast cancer. Leptin has been found to be involved in breast cancer progression. Therefore, novel approaches to antagonize biological effects of leptin are much needed. The objective of this study



Global Trade Item Number

SKUGTIN
68259-50ML04061837501449
43412-10MG04061835517565