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Merck
CN

44692

Apigenin 7-glucoside

analytical standard

Synonym(s):

4′,5,7-Trihydroxyflavone 7-glucoside, Apigenin-7-O-glucoside, Apigetrin, Cosmosiin

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About This Item

Empirical Formula (Hill Notation):
C21H20O10
CAS Number:
Molecular Weight:
432.38
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
209-430-5
Beilstein/REAXYS Number:
65669
MDL number:
Technical Service
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grade

analytical standard

Quality Level

assay

≥97.0% (HPLC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

OC[C@H]1O[C@@H](Oc2cc(O)c3C(=O)C=C(Oc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C21H20O10/c22-8-16-18(26)19(27)20(28)21(31-16)29-11-5-12(24)17-13(25)7-14(30-15(17)6-11)9-1-3-10(23)4-2-9/h1-7,16,18-24,26-28H,8H2/t16-,18-,19+,20-,21-/m1/s1

InChI key

KMOUJOKENFFTPU-QNDFHXLGSA-N

General description

Apigenin 7-glucoside is a flavone belonging to the class of polyphenols and is commonly found in Thymus species. It shows a broad spectrum of pharmacological properties such as antispasmodic, bactericidal, expectorant, antihelmintic, adstringent, antitussive and carminative agent.

Application

Apigenin 7-glucoside may be used as an analytical reference standard for the quantification of the analyte in Thymus species and Olea europaea using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: achillea ginkgo humulus hypericum melissa mentha pimpinella plantago salvia silybum thymus


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Determination of polyphenolic compounds by liquid chromatography-mass spectrometry in Thymus species
Boros B, et al.
Journal of Chromatography A, 1217(51), 7972-7980 (2010)
Janmejai K Srivastava et al.
Journal of agricultural and food chemistry, 55(23), 9470-9478 (2007-10-18)
Chamomile (Matricaria chamomilla), a popular herb valued for centuries as a traditional medicine, has been used to treat various human ailments; however, its anticancer activity is unknown. We evaluated the anticancer properties of aqueous and methanolic extracts of chamomile against
Laura Hanske et al.
The Journal of nutrition, 139(6), 1095-1102 (2009-05-01)
We investigated the impact of human intestinal microbiota on bioavailability of the flavone apigenin-7-glucoside (A7G) by comparing germ-free and human microbiota-associated (HMA) rats. First, the ability of the human intestinal microbiota to convert A7G was proven in vitro by incubating



Global Trade Item Number

SKUGTIN
44692-25MG-F04061833277201
44692-5MG-F04061835560615