49761
Spermidine
analytical standard
Synonym(s):
1,8-Diamino-4-azaoctane, N-(3-Aminopropyl)-1,4-diaminobutane
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About This Item
Linear Formula:
NH2(CH2)3NH(CH2)4NH2
CAS Number:
Molecular Weight:
145.25
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
204-689-0
Beilstein/REAXYS Number:
1698591
MDL number:
grade
analytical standard
Quality Level
assay
≥97.5% (NT), ≥99.0% (GC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
refractive index
n20/D 1.479 (lit.)
density
0.925 g/mL at 25 °C (lit.)
application(s)
cleaning products
cosmetics
food and beverages
personal care
format
neat
storage temp.
2-8°C
SMILES string
NCCCCNCCCN
InChI
1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2
InChI key
ATHGHQPFGPMSJY-UHFFFAOYSA-N
General description
Spermidine is a naturally occurring polyamine compound commonly found in food. It is essential for cell growth and survival.
Application
Spermidine may be used as one of the reference standard for the determination of spermidine in biological samples by high performance liquid chromatography-electrospray ionization–ion trap tandem mass spectrometry (HPLC–ESI–ITMS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T4 polynucleotide kinase activity.
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Disclaimer
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
233.6 °F - closed cup
flash_point_c
112 °C - closed cup
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Micro-scale strategy to detect spermine and spermidine by MALDI?TOF MS in foods and identification of apoptosis-related proteins by nano-flow UPLC?MS/MS after treatment with spermine and spermidine
Su H H, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 978, 131-137 (2015)
Determination of putrescine, cadaverine, spermidine and spermine in different chemical matrices by high performance liquid chromatography?electrospray ionization?ion trap tandem mass spectrometry (HPLC?ESI?ITMS/MS).
Ibarra A A G, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1002, 176-184 (2015)
Varun K Gupta et al.
Nature neuroscience, 16(10), 1453-1460 (2013-09-03)
Age-dependent memory impairment is known to occur in several organisms, including Drosophila, mouse and human. However, the fundamental cellular mechanisms that underlie these impairments are still poorly understood, effectively hampering the development of pharmacological strategies to treat the condition. Polyamines
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 49761-100MG | 04061832418094 |