51197
Sodium formate solution
suitable for LC-MS, LiChropur™
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About This Item
Linear Formula:
HCOONa
CAS Number:
Molecular Weight:
68.01
NACRES:
NB.21
UNSPSC Code:
41116105
Beilstein/REAXYS Number:
3723428
MDL number:
quality
LiChropur™
concentration
10 mM NaOH in isopropanol/water 1:1 (+0.2% HCOOH)
technique(s)
LC/MS: suitable
suitability
suitable for LC-MS
SMILES string
[Na+].[O-]C=O
InChI
1S/CH2O2.Na/c2-1-3;/h1H,(H,2,3);/q;+1/p-1
InChI key
HLBBKKJFGFRGMU-UHFFFAOYSA-M
General description
Sodium formate solution is commonly used as a mobile phase additive in liquid chromatography-mass spectrometry (LC-MS).
Features:
Features:
- Extensive QC testing ensures the highest specifications.
- Optimized to improve ionization and resolution.
- Extremely low levels of inorganic and organic impurities.
- Manufactured specifically for accurate and fast LC-MS.
Application
Sodium formate may be used as a mobile phase additive in the following:
- enantiomeric separation of acidic compounds by nano-liquid chromatography (Nano-LC) technique
- determination of ambrisentan enantiomers in commercial samples of active pharmaceutical ingredients (API) using high-performance liquid chromatography (HPLC) technique
Legal Information
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
Storage Class
12 - Non Combustible Liquids
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Anna Rocco et al.
Journal of separation science, 32(10), 1696-1703 (2009-04-17)
Some racemic nonsteroidal anti-inflammatory drugs, namely naproxen, indoprofen, ketoprofen, flurbiprofen, carprofen, cicloprofen, flunoxaprofen and suprofen were separated into their enantiomers by nano-LC. Chiral recognition was achieved adding to the mobile phase heptakis (2,3,6-tri-O-methyl)-beta-cyclodextrin (TM-beta-CD). Capillary columns of 100 microm id