66720
Methylene Blue hydrate
purum p.a., suitable for microscopy, ≥97.0% (calc. based on dry substance, AT)
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About This Item
Empirical Formula (Hill Notation):
C16H18ClN3S · xH2O
CAS Number:
Molecular Weight:
319.85 (anhydrous basis)
UNSPSC Code:
12171500
NACRES:
NA.32
PubChem Substance ID:
EC Number:
200-515-2
Beilstein/REAXYS Number:
3599847
MDL number:
grade
purum p.a.
Quality Level
assay
≥97.0% (calc. based on dry substance, AT)
form
powder
mol wt
319.85 g/mol (anhydrous basis)
concentration
≤100% (Methylthioninium chloride hydrate)
color
green to dark green
solubility
ethanol: 0.01 g/10 mL, blue to very deep blue
λmax
656-666 nm in water
suitability
suitable for microscopy
storage temp.
room temp
SMILES string
O.[Cl-].CN(C)c1ccc2N=C3C=C\C(C=C3Sc2c1)=[N+](/C)C
InChI
1S/C16H18N3S.ClH.H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;/h5-10H,1-4H3;1H;1H2/q+1;;/p-1
InChI key
WQVSELLRAGBDLX-UHFFFAOYSA-M
General description
Methylene Blue (MB) is a basic histological dye.
Application
Methylene Blue hydrate has been used:
- in the preparation of methylene blue (MB) solution to stain zymograms
- to label the injection site in the tissue slices
- to pre-treat mice via oral gavage to study its effects on noise-induced hearing loss
Biochem/physiol Actions
Methylene blue (MB) plays a key role in microbiology and pharmacology. It is mainly used in staining live organisms and in methemoglobinemia treatment. MB can be considered as a possible and safe vasoconstrictor. It has several applications in textile, paper and hair coloring sectors.
Other Notes
On the efficiency of methylene blue versus persulfate catalysis of polyacrylamide gels, as investigated by capillary zone electrophoresis
may contain up to 22% water
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Efficient removal of different basic dyes using graphene
Iqbala MZ, et al.
Desalination and Water Treatment, 68(3), 226-235 (2017)
UDP-Induced Phagocytosis and ATP-Stimulated Chemotactic Migration Are Impaired in STIM1-/- Microglia In Vitro and In Vivo
Lim HM, et al.
Mediators of Inflammation, 2017(3), e1687-e1687 (2017)
Methylene blue in photodynamic therapy: from basic mechanisms to clinical applications
Tardivo Jp, et al.
Photodiagnosis and Photodynamic Therapy, 2(3), 175-191 (2005)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 66720-100G | 04061835183906 |
| 66720-25G | 04061835183913 |
| 66720-500G | 04061832734606 |