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Merck
CN

72405

1,2-Dimethoxyethane

analytical standard

Synonym(s):

mono-Glyme, Dimethylglycol, Ethylene glycol dimethyl ether, Monoglyme

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About This Item

Linear Formula:
CH3OCH2CH2OCH3
CAS Number:
Molecular Weight:
90.12
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-794-9
Beilstein/REAXYS Number:
1209237
MDL number:
Technical Service
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grade

analytical standard

Quality Level

vapor density

3.1 (20 °C, vs air)

vapor pressure

48 mmHg ( 20 °C)

assay

≥99.7% (GC)

autoignition temp.

396 °F

shelf life

limited shelf life, expiry date on the label

contains

~0.01% 2,6-di-tert-butyl-4-methylphenol as stabilizer

expl. lim.

10.4 %

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.380

mp

−58 °C (lit.)

density

0.867 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

COCCOC

InChI

1S/C4H10O2/c1-5-3-4-6-2/h3-4H2,1-2H3

InChI key

XTHFKEDIFFGKHM-UHFFFAOYSA-N

General description

1,2-Dimethoxyethane is a water miscible solvent, used as an alternative for the hazardous organic solvents such as dioxane and tetrahydrofuran.
This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)

Application

1,2-Dimethoxyethane may be used as a solvent for the separation and determination of neutral sugars as 2,4- dinitrophenyl derivatives using high-performance liquid chromatography.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

41.0 °F - closed cup

flash_point_c

5 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

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Introduction to Organic Laboratory Techniques: A Small Scale Approach (2005)
Analysis of neutral sugars as dinitrophenyl-hydrazones by high-performance liquid chromatography
Karamanos.K.N, et al.
Journal of Chromatography A, 405, 221-228 (1987)
Shaokun Tang et al.
Bioresource technology, 129, 667-671 (2013-01-10)
Glymes (i.e. glycol diethers) were explored as alternative benign solvents for enzymatic reactions, specifically the lipase-catalyzed transesterification. Long-chain glymes were found highly compatible with immobilized Candida antarctica lipase B (iCALB), leading to higher enzyme activities and stabilities than t-butanol and



Global Trade Item Number

SKUGTIN
72405-1ML-F04061832861227
72405-5ML-F04061836962678