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791725

Citric acid

Name: Citric acid
Brand: SIAL

anhydrous grade, ACS reagent grade, ≥99.5%, Redi-Dri^™, free-flowing, crystals

Synonym(s):

2-Hydroxy-propane-1,2,3-tricarboxylic acid

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About This Item

Linear Formula:

HOC(COOH)(CH₂COOH)₂

CAS Number:

77-92-9

Molecular Weight:

192.12

Beilstein/REAXYS Number:

782061

NACRES:

NA.21

PubChem Substance ID:

329768287

UNSPSC Code:

12352100

EC Number:

201-069-1

MDL number:

MFCD00011669

eCl@ss:

39021801

Assay:

≥99.5%

Form:

crystals

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Properties

Product Name

Citric acid, anhydrous, free-flowing, Redi-Dri^™, ACS reagent, ≥99.5%

Quality Level

200

grade

ACS reagent, anhydrous

product line

Redi-Dri^™

assay

≥99.5%

form

crystals

quality

free-flowing

expl. lim.

8 %, 65 °F

impurities

Substances carbonizable by hot sulfuric acid, passes test

ign. residue

≤0.02%

pKa

(1) 3.13, (2) 4.76, (3) 6.4

mp

153-159 °C (lit.)

anion traces

chloride (Cl^-): ≤0.001%, oxalate (C₂O₄^2-): passes test (limit about 0.003%), phosphate (PO₄^3-): ≤0.001%, sulfate (SO₄^2-): ≤0.002%

cation traces

Fe: ≤3 ppm, Pb: ≤2 ppm

functional group

carboxylic acid, hydroxyl

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O

InChI

1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

KRKNYBCHXYNGOX-UHFFFAOYSA-N

Description

General description

Citric acid also called 2-hydroxy-propane-1,2,3-tricarboxylic acid, is a component of the tricarboxylic acid cycle in all organisms. Industrial production of citric acid use fungal, yeast and citrus fruit as the major source. Aspergillus niger is majorly used for citric acid production by fermentation Manganese inhibits fermentative production of citric acid Oral supplementation of citric acid promotes tricarboxylic acid cycle and oxidative phosphorylation in mitochondria, attenuating physical fatigue.

Application

Citric acidhas been used as a component of citrate buffer and Fe-free sauton′s medium. It has been used in hybridization chain reaction buffer for preequilibration of coverslips for testes sections.

Legal Information

Redi-Dri^™ is a trademark of Sigma-Aldrich Co. LLC

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

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pictograms

GHS07

signalword

Warning

hcodes

H319,H335

pcodes

P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Articles

Redi-Dri™ – The World of Free-flowing Hygroscopic Products

Redi-Dri™ prevents hygroscopic powders, such as inorganic salts, from absorbing moisture and forming clumps, leaving the salts free-flowing every time.

A comprehensive roadmap of murine spermatogenesis defined by single-cell RNA-seq

Green CD, et al.

Developmental Cell, 46(5), 651-667 (2018)

Biochemical studies of citric acid production and accumulation by Aspergillus niger mutants

Gupta S and Sharma CB

World Journal of Microbiology & Biotechnology, 18(5), 379-383 (2002)

Methylene blue exerts a neuroprotective effect against traumatic brain injury by promoting autophagy and inhibiting microglial activation

Zhao M, et al.

Molecular Medicine Reports, 13(1), 13-20 (2016)

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Global Trade Item Number

SKU	GTIN
791725-100G	04061832960579
791725-6X1KG	04061832950037
791725-12KG	04061832949925
791725-1KG	04061835555536
791725-2.5KG	04061832949970
791725-500G	04061832949987