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Merck
CN

906832

Dimethyl isosorbide

greener alternative

BioRenewable, ReagentPlus®, ≥99%

Synonym(s):

Isosorbide dimethyl ether, DMI, 1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol, 1,4:3,6-Dianhydrosorbitol 2,5-dimethyl ether, 2,5-Di-O-methyl-1,4:3,6-dianhydro-D-glucitol

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About This Item

Empirical Formula (Hill Notation):
C8H14O4
CAS Number:
Molecular Weight:
174.19
NACRES:
NA.07
UNSPSC Code:
12352005
Beilstein/REAXYS Number:
80854
MDL number:
Assay:
≥99%
Bp:
93-95 °C/0.1 mmHg (lit.)
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Quality Level

product line

ReagentPlus®

assay

≥99%

form

liquid

greener alternative product characteristics

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

dilution

(for general lab use)

refractive index

n20/D 1.461 (lit.)

bp

93-95 °C/0.1 mmHg (lit.)

density

1.15 g/mL at 25 °C (lit.)

greener alternative category

SMILES string

CO[C@H]1COC2[C@@H](COC12)OC

InChI

1S/C8H14O4/c1-9-5-3-11-8-6(10-2)4-12-7(5)8/h5-8H,3-4H2,1-2H3/t5-,6+,7-,8-/m1/s1

InChI key

MEJYDZQQVZJMPP-ULAWRXDQSA-N

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. Dimethyl isosorbide (DMI) is a biobased greener solvent and thus it aligns with "Use of Renewable Feedstocks" and "Safer Solvents and Auxiliaries". Click here for more information. Dimethyl isosorbide (DMI) is a sustainable alternative to dipolar aprotic solvents such as NMP and DMF, suitable for organic synthesis, as Baylis-Hillman reaction, and due to its high solubilization capacity when used as co-solvent for nonpolar drugs, make it an interesting compound for pharmaceutical and cosmetic industries as well.

Application

Dimethyl isosorbide may be used as an alternative solvent to NMP and/or DMF in some applications:
  • Polymer membranes preparation
  • Solvent in Baylis-Hillman reactions
  • Co-solvent to improve solubility of nonpolar compounds
  • Potential substitutes to short-chain glycol ethers

Features and Benefits

  • Bio-based
  • Made from Renewable Resource - straw
  • Non-toxic solvent
  • High solubility potential
  • High boiling point

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

240.8 °F - closed cup

flash_point_c

116 °C - closed cup



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Green Synthesis of Dimethyl Isosorbide
Pietro Tundo Prof. et al
ChemSusChem, 3, 566-570 (2010)



Global Trade Item Number

SKUGTIN
P8004-5G04061832851297
906832-100ML04065265099660
906832-1L04054839937255
906832-2.5L04054839937262
906832-4L04054839937279