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90984

Sucralose

analytical standard

Synonym(s):

1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside, E955, Trichlorosucrose

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About This Item

Empirical Formula (Hill Notation):
C12H19Cl3O8
CAS Number:
56038-13-2
Molecular Weight:
397.63
NACRES:
NA.24
E Number:
E955
PubChem Substance ID:
329769983
UNSPSC Code:
85151701
EC Number:
259-952-2
MDL number:
MFCD03648615
Beilstein/REAXYS Number:
3654410
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grade

analytical standard

Quality Level

100

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl

InChI

1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1

InChI key

BAQAVOSOZGMPRM-QBMZZYIRSA-N

General description

Sucralose is a derivative of sucrose, which is generally used as a non-nutritive sweetener in foods and beverages.
Sucralose, belonging to the class of synthetic sweeteners, is a noncarcinogenic taste enhancer, found to be 400-800 times sweeter than sucrose. It is not involved in inducing glycemic response and is virtually noncaloric. Sucralose is used as a part of a comprehensive portfolio of analytical standards to monitor natural and artificial sugar substitutes in the food and beverage industries. This product finds applications as a sweetener in a variety of food products and beverages including desserts, bakery products, canned fruits/vegetables, dressings, breakfast cereals, confectionery, medical foods, dietary supplements, etc.

Application

Sucralose may be used as an analytical reference standard for the quantification of the analyte in:
  • Commercial sugar-free products such as Splenda and Red Raspberry Diet Rite beverage using high performance anion-exchange (HPAE) chromatography coupled with pulsed amperometric detection (PAD).
  • Water and beverage samples using liquid chromatography/time-of-flight mass spectrometry (LC/TOF-MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

A synthetic sweet tastant detectable by humans. Activates T1R2/T1R3 sweet taste receptors on enteroendocrine cells and elicits increased hormonal secretion of glucagon-like peptide-1 and glucose-dependent insulinotrophic peptide.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH0973
BCCD3883
BCCC5473
BCCB8542
BCBX5165

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Determination of sucralose in splenda and a sugar-free beverage using high-performance anion-exchange chromatography with pulsed amperometric detection
Hanko PV, et al.
Journal of Agricultural and Food Chemistry, 52(14), 4375-4379 (2004)
An overview of the safety of sucralose
Grotz L.V and Munro C.I
Regulatory Toxicology and Pharmacology, 55(01), 1-5 (2009)
Food Analysis by HPLC, Second Edition (2000)
View All Related Papers

Global Trade Item Number

SKUGTIN
90984-100MG04061835561247