92574
Mefenamic acid
analytical standard
Synonym(s):
2-[(2,3-Dimethylphenyl)amino]benzoic acid, N-(2,3-Xylyl)anthranilic acid
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About This Item
Empirical Formula (Hill Notation):
C15H15NO2
CAS Number:
Molecular Weight:
241.29
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-513-1
MDL number:
grade
analytical standard
Quality Level
assay
≥98.5% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤1.0% water
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
SMILES string
Cc1cccc(Nc2ccccc2C(O)=O)c1C
InChI
1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)
InChI key
HYYBABOKPJLUIN-UHFFFAOYSA-N
Gene Information
human ... PTGS1(5742), PTGS2(5743)
Application
An NSAID. Circumvents MRP-mediated multidrug resistance. Specifically and significantly potentiates the cytotoxicity of anthracyclines as well as teniposide, VP-16 and vincristine.
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Renata Colombo et al.
Journal of environmental management, 167, 206-213 (2015-12-22)
Mefenamic acid (MEF) is a non-steroidal anti-inflammatory drug indicated for relief of mild to moderate pain, and for the treatment of primary dysmenorrhea. The presence of MEF in raw and sewage waters has been detected worldwide at concentrations exceeding the
Umang V Shah et al.
International journal of pharmaceutics, 472(1-2), 140-147 (2014-06-15)
The role of surface properties, influenced by particle processing, in particle-particle interactions (powder cohesion) is investigated in this study. Wetting behaviour of mefenamic acid was found to be anisotropic by sessile drop contact angle measurements on macroscopic (>1cm) single crystals
Harini Venkataraman et al.
Bioorganic & medicinal chemistry, 22(20), 5613-5620 (2014-07-08)
Cytochrome P450 BM3 mutants are promising biocatalysts for the production of drug metabolites. In the present study, the ability of cytochrome P450 BM3 mutants to produce oxidative metabolites of structurally related NSAIDs meclofenamic acid, mefenamic acid and tolfenamic acid was
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 92574-250MG | 04061833269916 |