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Merck
CN

95162

2,3,5,6-Tetramethylpyrazine

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C8H12N2
CAS Number:
Molecular Weight:
136.19
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
214-391-2
Beilstein/REAXYS Number:
113100
MDL number:
Technical Service
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grade

analytical standard

Quality Level

assay

≥98.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

bp

190 °C (lit.)

mp

77-80 °C (lit.), 85-87 °C

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

format

neat

SMILES string

Cc1nc(C)c(C)nc1C

InChI

1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3

InChI key

FINHMKGKINIASC-UHFFFAOYSA-N

General description

2,3,5,6-Tetramethylpyrazine is a flavor compound belonging to the class of pyrazines. It is found to be a main active ingredient of the traditional Chinese medicine, Chuanxiong and Ma-Huang herbs, used to treat asthma.

Application

2,3,5,6-Tetramethylpyrazine may be used as an analytical reference standard for the quantification of the analyte in Ephedrae herba and Ephedra sinica Stapf using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Applications of Microbial Engineering (2013)
Separation and determination of ephedrine alkaloids and tetramethylpyrazine in ephedra sinica Stapf by gas chromatography-mass spectrometry
Journal of Chromatographic Science, 39(9), 370-374 (2001)
Analysis of tetramethylpyrazine in Ephedrae herba by gas chromatography?mass spectrometry and high-performance liquid chromatography
Lv K, et al.
Journal of Chromatography A, 878(1), 147-152 (2000)



Global Trade Item Number

SKUGTIN
95162-100MG04061833315644