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A0230000

Adenine

Name: Adenine
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

6-Aminopurine, Vitamin B₄

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About This Item

Empirical Formula (Hill Notation):

C₅H₅N₅

CAS Number:

73-24-5

Molecular Weight:

135.13

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329770588

MDL number:

MFCD00041790

Beilstein/REAXYS Number:

5777

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Properties

biological source

synthetic

grade

pharmaceutical primary standard

agency

API family

adenine

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

mp

>360 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Nc1ncnc2[nH]cnc12

InChI

1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)

InChI key

GFFGJBXGBJISGV-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Adenine belongs to the group of purine alkaloids widely distributed in plant products and beverages. It can be used as an internal microbial marker for the determination of microbial protein synthesis.

Application

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P301 + P310 + P330

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

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Simultaneous determination of adenine and guanine in ruminant bacterial pellets by ion-pair HPLC

Moral dGP, et al.

Journal of Chromatography. B, Biomedical Sciences and Applications, 826(1-2), 257-260 (2005)

Determination of adenine, caffeine, theophylline and theobromine by HPLC with amperometric detection

Meyer A, et al.

Fresenius Journal of Analytical Chemistry, 356(3-4), 284-287 (1996)

Rilpivirine versus efavirenz with emtricitabine/tenofovir disoproxil fumarate in treatment-naïve HIV-1-infected patients with HIV-1 RNA ≤100,000 copies/mL: week 96 pooled ECHO/THRIVE subanalysis.

Georg Behrens et al.

AIDS patient care and STDs, 28(4), 168-175 (2014-03-26)

The once daily, single-tablet regimen (STR) combining rilpivirine (RPV), emtricitabine (FTC), and tenofovir disoproxil fumarate (TDF) provides a simplified treatment option for antiretroviral therapy (ART)-naïve patients with baseline HIV-1 RNA (BLVL) of ≤100,000 copies/mL. The aim of this analysis is

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Global Trade Item Number

SKU	GTIN
A0230000	04061833791240