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Merck
CN

B2635

Busulfan

analytical standard, for drug analysis

Synonym(s):

1,4-Butanediol dimethanesulfonate

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About This Item

Linear Formula:
CH3SO2O(CH2)4OSO2CH3
CAS Number:
Molecular Weight:
246.30
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-250-2
Beilstein/REAXYS Number:
1791786
MDL number:
Technical Service
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Quality Level

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

114-117 °C (lit.)

application(s)

forensics and toxicology
veterinary

format

neat

SMILES string

CS(=O)(=O)OCCCCOS(C)(=O)=O

InChI

1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3

InChI key

COVZYZSDYWQREU-UHFFFAOYSA-N

General description

Busulfan is a bifunctional alkylating agent, which may find application in the treatment of chronic granulocytic leukemia.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1A - Muta. 1B - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Blood and Marrow Stem Cell Transplantation: Principles, Practice, and Nursing Insights (1997)
Manabu Ozawa et al.
Biology of reproduction, 94(4), 92-92 (2016-03-18)
The F-box and leucine-rich repeat protein 10 (Fbxl10) gene encodes a protein that catalyzes demethylation of H3K4 and H3K36. In this study, we show the important roles of FBXL10 as a histone demethylase in sustainable sperm production using mice in
Edward A Copelan et al.
Blood, 122(24), 3863-3870 (2013-09-26)
Cyclophosphamide combined with total body irradiation (Cy/TBI) or busulfan (BuCy) are the most widely used myeloablative conditioning regimens for allotransplants. Recent data regarding their comparative effectiveness are lacking. We analyzed data from the Center for International Blood and Marrow Transplant



Global Trade Item Number

SKUGTIN
B2635-10G04061833426975
B2635-25G04061833426982