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BP021

Ampicillin trihydrate

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

D-(−)-α-Aminobenzylpenicillin

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About This Item

Empirical Formula (Hill Notation):
C16H19N3O4S · 3H2O
CAS Number:
7177-48-2
Molecular Weight:
403.45
EC Number:
200-709-7
UNSPSC Code:
41116107
NACRES:
NA.24
Beilstein/REAXYS Number:
5399534
MDL number:
MFCD00072036
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grade

pharmaceutical primary standard

API family

ampicillin

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

mp

198-200 °C (dec.) (lit.)

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

−20°C (−15°C to −25°C)

SMILES string

O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O

InChI

1S/C16H19N3O4S.3H2O/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;;;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);3*1H2/t9-,10-,11+,14-;;;/m1.../s1

InChI key

RXDALBZNGVATNY-CWLIKTDRSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ampicillin trihydrate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Co-fluampicil Oral Suspension
  • Co-fluampicil Capsules
  • Ticarcillin and Clavulanic Acid Infusion
  • Ampicillin Oral Suspension
  • Ampicillin Injection
  • Ampicillin Capsules
  • Amoxicillin Veterinary Oral Powder
  • Amoxicillin Oily Injections
  • Amoxicillin Injection
  • Amoxicillin Oral Suspension
  • Amoxicillin Capsules
  • Amoxicillin Tablets

    • Biochem/physiol Actions

    A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.

    Packaging

    Unit quantity: 500 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

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    pictograms

    Health hazardExclamation mark
    GHS08,GHS07

    signalword

    Danger

    Hazard Classifications

    Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

    target_organs

    Respiratory system

    Storage Class

    11 - Combustible Solids

    wgk

    WGK 2

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    Regulatory Information

    涉药品监管产品

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    Global Trade Item Number

    SKUGTIN
    BP02104061835277803